Carlos R Tonussi
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Explore the profile of Carlos R Tonussi including associated specialties, affiliations and a list of published articles.
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8
Citations
54
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Recent Articles
1.
Lucena F, Callado de Oliveira D, Noroes M, Mujica E, Melleu F, Benedet P, et al.
Life Sci
. 2019 Sep;
236:116860.
PMID: 31518605
Aims: Intrathecal injection of morphine presents analgesic and antiedematogenic effects in rats. However, it is unknown whether tramadol, which possess a mixed mechanism of action, can also produce analgesic and...
2.
Florentino I, da Silva D, Martins J, da Silva T, Santos F, Tonussi C, et al.
Inflammopharmacology
. 2016 Sep;
24(5):265-275.
PMID: 27671330
Chronic inflammation is a world health problem. There is a need to develop new anti-inflammatory and analgesic drugs with improved activity and reduced side effects. In this context, the aim...
3.
Florentino I, Nascimento M, Galdino P, De Brito A, da Rocha F, Tonussi C, et al.
An Acad Bras Cienc
. 2013 Sep;
85(3):987-97.
PMID: 24068088
The Hydrocotyle umbellata L. is a specimen of the Araliaceae family popularly known as acariçoba. Its indications in folk medicine include treatment of skin ulcers, and rheumatism. The aim of...
4.
Foletto V, Martins M, Tonussi C
Anesth Analg
. 2012 Dec;
116(1):232-8.
PMID: 23223096
Background: A previous study indicated that intrathecal administration of morphine reduces experimental inflammatory edema in rats by activating the nitric oxide/cyclic guanosine monophosphate pathway. This evidence supports the hypothesis that...
5.
Bastos L, Tonussi C
Eur J Pain
. 2009 May;
14(2):113-9.
PMID: 19423371
Animal models for mechanical pressure or heat nociception usually only measure the threshold response latency. In this study, the effect of typical sensitising treatments on the lasting nocifensive behaviour elicited...
6.
Daher J, de Melo M, Tonussi C
Life Sci
. 2005 Mar;
76(20):2349-59.
PMID: 15748628
We investigated the effect of serotonergic agonists and antagonists injected intrathecally by direct punction of the spinal cord at the lumbar level (between L5-L6) on peripheral inflammatory edema. Edema was...
7.
Comparison of two PBR ligands with classical antiinflammatory drugs in LPS-induced arthritis in rats
Bressan E, Farges R, Ferrara P, Tonussi C
Life Sci
. 2003 Apr;
72(23):2591-601.
PMID: 12672505
The antinociceptive and anti-edematogenic effects of peripheral benzodiazepine receptor (PBR) ligands, Ro5-4864 (7-chloro-5- (4-chlorophenyl)-1,3-dihydro-1-methyl-2-H-1,4-benzodiazepine-2) and PK11195 (1-(2-chlorophenyl)-N-methyl-N(1-methylpropyl)-3-isoquinoline carboxamide), were studied in an experimental model of carrageenan/LPS -induced arthritis in rats....
8.
Tonussi C, Ferreira S
Pain
. 1999 Jul;
82(1):81-87.
PMID: 10422663
Tumour necrosis factor-alpha (TNF alpha) was studied in the carrageenin (CG) induced knee-joint incapacitation, and also in mediating recurrent incapacitation response in knee-joints previously exposed to an inflammatory attack. CG...