Carlos Lafourcade
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Explore the profile of Carlos Lafourcade including associated specialties, affiliations and a list of published articles.
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14
Citations
481
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Recent Articles
1.
Caviedes A, Maturana B, Corvalan K, Engler A, Gordillo F, Varas-Godoy M, et al.
Cell Death Dis
. 2021 Jan;
12(1):4.
PMID: 33414434
Cell death by glutamate excitotoxicity, mediated by N-methyl-D-aspartate (NMDA) receptors, negatively impacts brain function, including but not limited to hippocampal neurons. The NF-κB transcription factor (composed mainly of p65/p50 subunits)...
2.
Luarte A, Henzi R, Fernandez A, Gaete D, Cisternas P, Pizarro M, et al.
Cells
. 2020 Apr;
9(4).
PMID: 32290095
In the last few decades, it has been established that astrocytes play key roles in the regulation of neuronal morphology. However, the contribution of astrocyte-derived small extracellular vesicles (sEVs) to...
3.
Rambousek L, Gschwind T, Lafourcade C, Paterna J, Dib L, Fritschy J, et al.
Sci Rep
. 2020 Mar;
10(1):3760.
PMID: 32111960
Epilepsy is a widespread neurological disease characterized by abnormal neuronal activity resulting in recurrent seizures. There is mounting evidence that a circadian system disruption, involving clock genes and their downstream...
4.
Gschwind T, Lafourcade C, Gfeller T, Zaichuk M, Rambousek L, Knuesel I, et al.
Eur J Neurosci
. 2018 Jun;
47(12):1534-1562.
PMID: 29862588
Aberrant epileptic activity is detectable at early disease stages in Alzheimer's disease (AD) patients and in AD mouse models. Here, we investigated in young ArcticAβ mice whether AD-like pathology renders...
5.
Luarte A, Cisternas P, Caviedes A, Batiz L, Lafourcade C, Wyneken U, et al.
Stem Cells Int
. 2017 Oct;
2017:1719050.
PMID: 29081809
Repetitive stress negatively affects several brain functions and neuronal networks. Moreover, adult neurogenesis is consistently impaired in chronic stress models and in associated human diseases such as unipolar depression and...
6.
Caviedes A, Varas-Godoy M, Lafourcade C, Sandoval S, Bravo-Alegria J, Kaehne T, et al.
Front Cell Neurosci
. 2017 Jul;
11:180.
PMID: 28725180
Nitric oxide exerts important regulatory functions in various brain processes. Its synthesis in neurons has been most commonly ascribed to the neuronal nitric oxide synthase (nNOS) isoform. However, the endothelial...
7.
Caviedes A, Lafourcade C, Soto C, Wyneken U
Curr Pharm Des
. 2017 Jan;
23(21):3154-3163.
PMID: 28078988
Background: Mood disorders, consisting of unipolar and bipolar depression, are complex diseases characterized by depressed mood and anhedonia. These core symptoms are accompanied in a varying manner by anxiety, several...
8.
Palacios J, Cifuentes F, Valderrama J, Benites J, Rios D, Gonzalez C, et al.
Oxid Med Cell Longev
. 2016 Sep;
2016:3939540.
PMID: 27672420
The vascular endothelium plays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways....
9.
Lafourcade C, Ramirez J, Luarte A, Fernandez A, Wyneken U
J Exp Neurosci
. 2016 Aug;
10(Suppl 1):1-9.
PMID: 27547038
Astrocytes use gliotransmitters to modulate neuronal function and plasticity. However, the role of small extracellular vesicles, called exosomes, in astrocyte-to-neuron signaling is mostly unknown. Exosomes originate in multivesicular bodies of...
10.
Deprez F, Vogt F, Floriou-Servou A, Lafourcade C, Rudolph U, Tyagarajan S, et al.
Eur J Neurosci
. 2016 Jul;
44(5):2258-71.
PMID: 27364953
Alterations of neuronal activity due to changes in GABAA receptors (GABAA R) mediating tonic inhibition influence different hippocampal functions. Gabra5-null mice and α5 subunit((H105R)) knock-in mice exhibit signs of hippocampal...