Carlos Hedman
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Explore the profile of Carlos Hedman including associated specialties, affiliations and a list of published articles.
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9
Citations
64
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Recent Articles
1.
Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie
Betancor M, Marin B, Otero A, Hedman C, Romero A, Barrio T, et al.
Vet Res
. 2023 Oct;
54(1):89.
PMID: 37794450
The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the...
2.
Marin B, Otero A, Lugan S, Espinosa J, Marin-Moreno A, Vidal E, et al.
Sci Rep
. 2021 Sep;
11(1):17428.
PMID: 34465826
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrP accumulation was detected in porcine tissues after the inoculation of certain scrapie...
3.
Otero A, Hedman C, Fernandez-Borges N, Erana H, Marin B, Monzon M, et al.
Mol Neurobiol
. 2019 Mar;
56(9):6501-6511.
PMID: 30847740
Specific variations in the amino acid sequence of prion protein (PrP) are key determinants of susceptibility to prion diseases. We previously showed that an amino acid substitution specific to canids...
4.
Hedman C, Otero A, Douet J, Lacroux C, Lugan S, Filali H, et al.
PLoS One
. 2018 Jul;
13(7):e0199914.
PMID: 29975760
Bovine spongiform encephalopathy (BSE) can be efficiently transmitted to pigs via intracerebral inoculation. A clear link has been established between the consumption of products of bovine origin contaminated with the...
5.
Otero A, Bolea R, Hedman C, Fernandez-Borges N, Marin B, Lopez-Perez O, et al.
Mol Neurobiol
. 2017 Dec;
55(7):6182-6192.
PMID: 29264770
While prion diseases have been described in numerous species, some, including those of the Canidae family, appear to show resistance or reduced susceptibility. A better understanding of the factors underlying...
6.
Bolea R, Hedman C, Lopez-Perez O, Marin B, Vidal E, Pumarola M, et al.
J Gen Virol
. 2017 Sep;
98(10):2628-2634.
PMID: 28920852
Multiple theories exist regarding the origin of bovine spongiform encephalopathy (BSE). An early and prominent theory proposed that BSE was the result of the adaptation of sheep scrapie to cattle....
7.
Hedman C, Bolea R, Marin B, Cobriere F, Filali H, Vazquez F, et al.
Vet Res
. 2016 Jan;
47:14.
PMID: 26742788
Experimental transmission of the bovine spongiform encephalopathy (BSE) agent has been successfully reported in pigs inoculated via three simultaneous distinct routes (intracerebral, intraperitoneal and intravenous). Sheep derived BSE (Sh-BSE) is...
8.
Filali H, Martin-Burriel I, Harders F, Varona L, Hedman C, Mediano D, et al.
BMC Genomics
. 2014 Jan;
15:59.
PMID: 24450868
Background: Prion diseases are characterized by the accumulation of the pathogenic PrPSc protein, mainly in the brain and the lymphoreticular system. Although prions multiply/accumulate in the lymph nodes without any...
9.
Hedman C, Lyahyai J, Filali H, Marin B, Serrano C, Monleon E, et al.
Vet Microbiol
. 2012 Apr;
159(1-2):23-32.
PMID: 22482719
Neuronal loss is one of the characteristics of scrapie neuropathology. Previous analysis of brains from sheep naturally infected with scrapie that were in a terminal stage did not detect a...