Carlos Castilla
Overview
Explore the profile of Carlos Castilla including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
161
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0
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Recent Articles
1.
Cabello R, Bueno-Serrano G, Arteche A, Villacampa J, Castilla C, Carnero C, et al.
Adv Med Educ Pract
. 2024 Jun;
15:451-459.
PMID: 38826693
Introduction: Learning laparoscopy (LAP) is challenging and requires different skills to conventional open surgery. There is a recognized need for a standardized laparoscopic training framework within urology to overcome these...
2.
Ferrer-Bonsoms J, Gimeno M, Olaverri D, Sacristan P, Lobato C, Castilla C, et al.
NAR Genom Bioinform
. 2022 Sep;
4(3):lqac067.
PMID: 36128425
Alternative splicing (AS) plays a key role in cancer: all its hallmarks have been associated with different mechanisms of abnormal AS. The improvement of the human transcriptome annotation and the...
3.
Gimeno M, Jose-Eneriz E, Rubio A, Garate L, Miranda E, Castilla C, et al.
Cancers (Basel)
. 2022 Jul;
14(13).
PMID: 35805023
Recent functional genomic screens—such as CRISPR-Cas9 or RNAi screening—have fostered a new wave of targeted treatments based on the concept of synthetic lethality. These approaches identified LEthal Dependencies (LEDs) by...
4.
Carazo F, Bertolo C, Castilla C, Cendoya X, Campuzano L, Serrano D, et al.
Cancers (Basel)
. 2020 Jul;
12(7).
PMID: 32645997
The development of predictive biomarkers of response to targeted therapies is an unmet clinical need for many antitumoral agents. Recent genome-wide loss-of-function screens, such as RNA interference (RNAi) and CRISPR-Cas9...
5.
Ferrer-Bonsoms J, Cassol I, Fernandez-Acin P, Castilla C, Carazo F, Rubio A
Sci Rep
. 2020 Jan;
10(1):1069.
PMID: 31974522
The advent of RNA-seq technologies has switched the paradigm of genetic analysis from a genome to a transcriptome-based perspective. Alternative splicing generates functional diversity in genes, but the precise functions...
6.
Anguiano M, Morales X, Castilla C, Pena A, Ederra C, Martinez M, et al.
PLoS One
. 2020 Jan;
15(1):e0220019.
PMID: 31945053
The migration of cancer cells is highly regulated by the biomechanical properties of their local microenvironment. Using 3D scaffolds of simple composition, several aspects of cancer cell mechanosensing (signal transduction,...
7.
Castilla C, Maska M, Sorokin D, Meijering E, Ortiz-de-Solorzano C
IEEE Trans Med Imaging
. 2018 Oct;
38(3):862-872.
PMID: 30296215
We present a 3D bioimage analysis workflow to quantitatively analyze single, actin-stained cells with filopodial protrusions of diverse structural and temporal attributes, such as number, length, thickness, level of branching,...
8.
Anguiano M, Castilla C, Maska M, Ederra C, Pelaez R, Morales X, et al.
PLoS One
. 2017 Feb;
12(2):e0171417.
PMID: 28166248
Microfluidic devices are becoming mainstream tools to recapitulate in vitro the behavior of cells and tissues. In this study, we use microfluidic devices filled with hydrogels of mixed collagen-Matrigel composition...
9.
Anguiano M, Castilla C, Maska M, Ederra C, Fernandez-Marques J, Pelaez R, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2016 Jan;
2015:8139-42.
PMID: 26738183
The geometry of 3D collagen networks is a key factor that influences the behavior of live cells within extra-cellular matrices. This paper presents a method for automatic quantification of the...
10.
Secchi M, Pettinari R, Mercapide C, Bracco R, Castilla C, Cassone E, et al.
Liver Int
. 2009 Sep;
30(1):85-93.
PMID: 19747191
Background: The management of hydatid liver disease (HLD) includes various nonsurgical and surgical treatment options. Methods: The purpose of the present longitudinal study was to report the changes in surgical...