Carlos Alberto Pereira Tavares
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Explore the profile of Carlos Alberto Pereira Tavares including associated specialties, affiliations and a list of published articles.
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Citations
323
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Recent Articles
1.
de Sousa Vieira Tavares G, Mendonca D, Pagliara Lage D, Granato J, Ottoni F, Ludolf F, et al.
Basic Clin Pharmacol Toxicol
. 2018 Feb;
123(3):236-246.
PMID: 29481714
In this study, a quinoline derivate, clioquinol (5-chloro-7-iodoquinolin-8-ol), was evaluated against Leishmania amazonensis and Leishmania infantum promastigotes and amastigotes. The cytotoxicity in murine macrophages and human red blood cells, as...
2.
Mendonca D, Pagliara Lage D, Calixto S, Ottoni F, de Sousa Vieira Tavares G, Ludolf F, et al.
Parasitol Res
. 2017 Dec;
117(2):391-403.
PMID: 29248978
Leishmaniasis has become a significant public health issue in several countries in the world. New products have been identified to treat against the disease; however, toxicity and/or high cost is...
3.
Duarte M, Pagliara Lage D, Martins V, Costa L, Carvalho A, Ludolf F, et al.
Immunobiology
. 2016 Oct;
222(2):251-260.
PMID: 27693018
In the present study, two proteins cloned from Leishmania braziliensis species, a hypothetical protein (LbHyp) and the eukaryotic initiation factor 5a (EiF5a), were evaluated to protect BALB/c mice against L....
4.
Duarte M, Pagliara Lage D, Martins V, Chavez-Fumagalli M, Roatt B, Menezes-Souza D, et al.
Rev Soc Bras Med Trop
. 2016 Sep;
49(4):398-407.
PMID: 27598624
Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide. Although chemotherapy has been widely used to treat this disease, problems related to the development of parasite resistance...
5.
Duarte M, Lage L, Pagliara Lage D, Martins V, Carvalho A, Roatt B, et al.
Parasitol Int
. 2016 Jul;
65(6 Pt A):728-736.
PMID: 27425599
New therapeutics are urgently needed to treat visceral leishmaniasis (VL). Due to the fact that drug discovery is a long and expensive process, the development of delivery systems to carry...
6.
Lage L, Barichello J, Pagliara Lage D, Mendonca D, Carvalho A, Rodrigues M, et al.
Parasitol Res
. 2016 Jul;
115(11):4083-4095.
PMID: 27365053
The current treatment of leishmaniasis has been hampered due to the high toxicity of the available drugs and long duration protocols, which often lead to its abandonment. In the present...
7.
Pagliara Lage D, Martins V, Duarte M, Costa L, de Sousa Vieira Tavares G, Ramos F, et al.
Acta Trop
. 2016 Mar;
158:220-230.
PMID: 26976272
Vaccination can be considered the most cost-effective strategy to control neglected diseases, but nowadays there is not an effective vaccine available against leishmaniasis. In the present study, a vaccine based...
8.
Duarte M, Lage L, Pagliara Lage D, Mesquita J, Salles B, Lavorato S, et al.
Vet Parasitol
. 2016 Feb;
217:81-8.
PMID: 26827866
The development of new therapeutic strategies to treat leishmaniasis has become a priority. In the present study, the antileishmanial activity of 8-hydroxyquinoline (8-HQN) was investigated against in vitro promastigotes and...
9.
Ferraz Coelho E, Costa L, Pagliara Lage D, Martins V, Garde E, de Jesus Pereira N, et al.
Vet Parasitol
. 2016 Jan;
215:63-71.
PMID: 26790739
Serological diagnostic tests for canine and human leishmaniasis present problems related with their sensitivity and/or specificity. Recently, an immunoproteomic approach performed with Leishmania infantum proteins identified new parasite antigens. In...
10.
Martins V, Pagliara Lage D, Duarte M, Costa L, Garde E, Rodrigues M, et al.
Acta Trop
. 2015 Nov;
154:73-81.
PMID: 26593442
The present study aimed to evaluate a new Leishmania-specific hypothetical protein, LiHyT, as a vaccine candidate against VL. The immunogenicity of the recombinant protein (rLiHyT) plus saponin was evaluated in...