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Carlo Bonchi

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Articles 10
Citations 363
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Recent Articles
1.
Runci F, Bonchi C, Frangipani E, Visaggio D, Visca P
Antimicrob Agents Chemother . 2016 Nov; 61(1). PMID: 27799219
Biofilm-associated infections caused by Acinetobacter baumannii are extremely recalcitrant to antibiotic treatment. We report that A. baumannii develops a mature biofilm when grown in complement-free human serum (HS). We demonstrate...
2.
Minandri F, Imperi F, Frangipani E, Bonchi C, Visaggio D, Facchini M, et al.
Infect Immun . 2016 Jun; 84(8):2324-2335. PMID: 27271740
Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections in cystic fibrosis patients. Iron is essential for bacterial growth, and P. aeruginosa expresses multiple iron uptake...
3.
Deodato D, Maccari G, De Luca F, Sanfilippo S, Casian A, Martini R, et al.
J Med Chem . 2016 Apr; 59(8):3854-66. PMID: 27045868
We recently identified a novel family of macrocyclic amidinoureas showing potent antifungal activity against Candida spp. In this study, we demonstrate the fungicidal effect of these compounds as well as...
4.
Visaggio D, Pasqua M, Bonchi C, Kaever V, Visca P, Imperi F
Front Microbiol . 2015 Sep; 6:902. PMID: 26379660
In Pseudomonas aeruginosa the Gac signaling system and the second messenger cyclic diguanylate (c-di-GMP) participate in the control of the switch between planktonic and biofilm lifestyles, by regulating the production...
5.
Bonchi C, Frangipani E, Imperi F, Visca P
Antimicrob Agents Chemother . 2015 Jul; 59(9):5641-6. PMID: 26149986
Gallium is an iron mimetic which has recently been repurposed as an antibacterial agent due to its capability to disrupt bacterial iron metabolism. In this study, the antibacterial activity of...
6.
Gentile V, Frangipani E, Bonchi C, Minandri F, Runci F, Visca P
Pathogens . 2014 Dec; 3(3):704-19. PMID: 25438019
Acinetobacter baumannii is an emerging nosocomial pathogen, responsible for infection outbreaks worldwide. The pathogenicity of this bacterium is mainly due to its multidrug-resistance and ability to form biofilm on abiotic...
7.
Frangipani E, Bonchi C, Minandri F, Imperi F, Visca P
Antimicrob Agents Chemother . 2014 Jun; 58(9):5572-5. PMID: 24957826
Gallium (Ga) is an iron mimetic that has successfully been repurposed for antibacterial chemotherapy. To improve the antibacterial potency of Ga on Pseudomonas aeruginosa, the effect of complexation with a...
8.
Minandri F, Bonchi C, Frangipani E, Imperi F, Visca P
Future Microbiol . 2014 Apr; 9(3):379-97. PMID: 24762310
Gallium has a long history as a diagnostic and chemotherapeutic agent. The pharmacological properties of Ga(III) rely on chemical mimicry; when Ga(III) is exogenously supplied to living cells it can...
9.
Bonchi C, Imperi F, Minandri F, Visca P, Frangipani E
Biofactors . 2014 Feb; 40(3):303-12. PMID: 24532037
While the occurrence and spread of antibiotic resistance in bacterial pathogens is vanishing current anti-infective therapies, the antibiotic discovery pipeline is drying up. In the last years, the repurposing of...
10.
Visca P, Bonchi C, Minandri F, Frangipani E, Imperi F
Antimicrob Agents Chemother . 2013 Apr; 57(5):2432-3. PMID: 23580579
No abstract available.