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Carlee R Giesige

Explore the profile of Carlee R Giesige including associated specialties, affiliations and a list of published articles. Areas
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Citations 108
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Recent Articles
1.
Kastenschmidt J, Coulis G, Farahat P, Pham P, Rios R, Cristal T, et al.
Cell Rep . 2021 Apr; 35(2):108997. PMID: 33852849
Despite the well-accepted view that chronic inflammation contributes to the pathogenesis of Duchenne muscular dystrophy (DMD), the function and regulation of eosinophils remain an unclear facet of type II innate...
2.
Giesige C, Wallace L, Heller K, Eidahl J, Saad N, Fowler A, et al.
JCI Insight . 2018 Nov; 3(22). PMID: 30429376
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant or digenic disorder linked to derepression of the toxic DUX4 gene in muscle. There is currently no pharmacological treatment. The emergence of...
3.
Eidahl J, Giesige C, Domire J, Wallace L, Fowler A, Guckes S, et al.
Hum Mol Genet . 2017 Feb; 25(20):4577-4589. PMID: 28173143
D4Z4 repeats are present in at least 11 different mammalian species, including humans and mice. Each repeat contains an open reading frame encoding a double homeodomain (DUX) family transcription factor....
4.
Ansseau E, Domire J, Wallace L, Eidahl J, Guckes S, Giesige C, et al.
PLoS One . 2015 Mar; 10(3):e0118813. PMID: 25742305
The DUX4 gene, encoded within D4Z4 repeats on human chromosome 4q35, has recently emerged as a key factor in the pathogenic mechanisms underlying Facioscapulohumeral muscular dystrophy (FSHD). This recognition prompted...