Carla Cuni-Lopez
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Explore the profile of Carla Cuni-Lopez including associated specialties, affiliations and a list of published articles.
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10
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104
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Recent Articles
1.
Cuni-Lopez C, Stewart R, Okano S, Redlich G, Appleby M, White A, et al.
Sci Rep
. 2025 Mar;
15(1):8296.
PMID: 40064964
The scarcity of effective biomarkers and therapeutic strategies for predicting disease onset and progression in neurodegenerative diseases such as Alzheimer's disease (AD) is a major challenge. Conventional drug discovery approaches...
2.
Odendaal L, Quek H, Cuni-Lopez C, White A, Stewart R
Biomedicines
. 2025 Jan;
13(1).
PMID: 39857829
The escalating issue of air pollution contributes to an alarming number of premature fatalities each year, thereby posing a significant threat to global health. The focus of recent research has...
3.
Cuni-Lopez C, Stewart R, Oikari L, Nguyen T, Roberts T, Sun Y, et al.
J Neuroinflammation
. 2024 Apr;
21(1):90.
PMID: 38600570
No abstract available.
4.
Cuni-Lopez C, Stewart R, Oikari L, Nguyen T, Roberts T, Sun Y, et al.
J Neuroinflammation
. 2024 Feb;
21(1):50.
PMID: 38365833
Background: Alzheimer's disease (AD) is an incurable neurodegenerative disorder with a rapidly increasing prevalence worldwide. Current approaches targeting hallmark pathological features of AD have had no consistent clinical benefit. Neuroinflammation...
5.
Chaves J, Wasielewska J, Cuni-Lopez C, Rantanen L, Lee S, Koistinaho J, et al.
Neurotherapeutics
. 2024 Jan;
21(1):e00299.
PMID: 38241156
The blood-brain barrier (BBB) has a key function in maintaining homeostasis in the brain, partly modulated by transporters, which are highly expressed in brain endothelial cells (BECs). Transporters mediate the...
6.
Cuni-Lopez C, Stewart R, White A, Quek H
J Neuroimmunol
. 2023 Jan;
375:578017.
PMID: 36657374
Microglia have an increasingly well-recognised role in the pathogenesis of neurodegenerative diseases, thereby becoming attractive therapeutic targets. However, the development of microglia-targeted therapeutics for neurodegeneration has had limited success. This...
7.
Rantanen L, Bitar M, Lampinen R, Stewart R, Quek H, Oikari L, et al.
Cells
. 2022 Oct;
11(20).
PMID: 36291125
An early symptom of Alzheimer's disease (AD) is an impaired sense of smell, for which the molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived (ONS) cells from people...
8.
Quek H, Cuni-Lopez C, Stewart R, Lim Y, Roberts T, White A
STAR Protoc
. 2022 Oct;
3(4):101747.
PMID: 36201317
Microglia are implicated in most neurodegenerative diseases. Here, we present a robust and efficient protocol to differentiate monocyte-derived microglia-like cells (MDMi) from whole blood. The protocol consists of three parts....
9.
Cuni-Lopez C, Stewart R, Quek H, White A
Cells
. 2022 May;
11(10).
PMID: 35626698
Neurodegenerative diseases are deteriorating conditions of the nervous system that are rapidly increasing in the ageing population. Increasing evidence suggests that neuroinflammation, largely mediated by microglia, the resident immune cells...
10.
Quek H, Cuni-Lopez C, Stewart R, Colletti T, Notaro A, Nguyen T, et al.
J Neuroinflammation
. 2022 Mar;
19(1):58.
PMID: 35227277
Background: Amyotrophic lateral sclerosis (ALS) is a multifactorial neurodegenerative disease characterised by the loss of upper and lower motor neurons. Increasing evidence indicates that neuroinflammation mediated by microglia contributes to...