Carl E Ruby
Overview
Explore the profile of Carl E Ruby including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
970
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0
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Recent Articles
1.
Hambly J, Ruby C, Mourich D, Bracha S, Dolan B
Vet Sci
. 2023 May;
10(5).
PMID: 37235419
The emergence of immunotherapy for the treatment of human cancers has heralded a new era in oncology, one that is making its way into the veterinary clinic. As the immune...
2.
Van Fossen E, Grutzius S, Ruby C, Mourich D, Cebra C, Bracha S, et al.
Front Chem
. 2022 Mar;
10:835229.
PMID: 35265586
A critical step in developing therapeutics for oxidative stress-related pathologies is the ability to determine which specific modified protein species are innocuous by-products of pathology and which are causative agents....
3.
Weinman M, Ramsey S, Leeper H, Brady J, Schlueter A, Stanisheuski S, et al.
Cancer Cell Int
. 2021 May;
21(1):245.
PMID: 33933069
Background: Osteosarcoma patients often experience poor outcomes despite chemotherapy treatment, likely due in part to various mechanisms of tumor cell innate and/or acquired drug resistance. Exosomes, microvesicles secreted by cells,...
4.
Duckett M, Curran K, Leeper H, Ruby C, Bracha S
Vet Comp Oncol
. 2021 Jan;
19(1):61-68.
PMID: 33448618
Fasting has been shown to decrease chemotherapy-associated adverse events (AEs), in part through insulin-like growth factor (IGF-1) reduction, and may induce a protective effect on normal cells during chemotherapy treatment...
5.
Brady J, Troyer R, Ramsey S, Leeper H, Yang L, Maier C, et al.
Transl Oncol
. 2018 Jul;
11(5):1137-1146.
PMID: 30053712
Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be...
6.
Troyer R, Ruby C, Goodall C, Yang L, Maier C, Albarqi H, et al.
Exp Cell Res
. 2017 Jul;
358(2):369-376.
PMID: 28712929
Background: Canine osteosarcoma (OSA) is the most common cancer of the appendicular skeleton and is associated with high metastatic rate to the lungs and poor prognosis. Recent studies have shown...
7.
Goldufsky J, Sivendran S, Harcharik S, Pan M, Bernardo S, Stern R, et al.
Oncolytic Virother
. 2016 Aug;
2:31-46.
PMID: 27512656
The use of oncolytic viruses to treat cancer is based on the selection of tropic tumor viruses or the generation of replication selective vectors that can either directly kill infected...
8.
Turturro S, Najor M, Ruby C, Cobleigh M, Abukhdeir A
Breast Cancer Res Treat
. 2016 Feb;
156(1):33-43.
PMID: 26915040
A review of the literature finds that women diagnosed with breast cancer, who were on an aspirin regimen, experienced a decreased risk of distant metastases and death. Several recent studies...
9.
Kohlhapp F, Broucek J, Hughes T, Huelsmann E, Lusciks J, Zayas J, et al.
J Immunother Cancer
. 2015 May;
3:18.
PMID: 25992289
Background: Melanoma is one of the few types of cancer with an increasing annual incidence. While a number of immunotherapies for melanoma have been associated with significant clinical benefit, including...
10.
Goldufsky J, Wood S, Hajihossainlou B, Rehman T, Majdobeh O, Kaufman H, et al.
J Med Microbiol
. 2015 Jan;
64(Pt 2):164-73.
PMID: 25627204
In patients with malignancy, the major barrier to achieving complete response is emergence of resistance to current chemotherapeutic agents. One of the major mechanisms by which tumour cells become resistant...