Carl Bjorkholm
Overview
Explore the profile of Carl Bjorkholm including associated specialties, affiliations and a list of published articles.
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14
Citations
554
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Recent Articles
1.
Gannedahl A, Bjorkholm C, Leval A, Cars T, Hellner C, Lundberg J
J Affect Disord
. 2024 Jun;
362:96-103.
PMID: 38914164
Background: Population-based surveys suggest that low socioeconomic status (SES) is associated with higher prevalence of depressive symptoms, while their healthcare utilization is not necessarily higher. Objective: To investigate the association...
2.
Lundberg J, Cars T, Lampa E, Ekholm Selling K, Leval A, Gannedahl A, et al.
JAMA Psychiatry
. 2023 Aug;
80(12):1218-1225.
PMID: 37585196
Importance: Major depressive disorder (MDD) is an important risk factor of suicidal behavior, but the added burden of suicidal behavior and MDD on the patient and societal level, including all-cause...
3.
Lundberg J, Cars T, Loov S, Soderling J, Sundstrom J, Tiihonen J, et al.
JAMA Psychiatry
. 2022 Dec;
80(2):167-175.
PMID: 36515938
Importance: The totality of the societal and individual impact of treatment-resistant depression (TRD) is unknown, as is the potential to prognosticate TRD. The generalizability of many observational studies on TRD...
4.
Lundberg J, Cars T, Loov S, Soderling J, Tiihonen J, Leval A, et al.
Acta Psychiatr Scand
. 2022 Feb;
146(1):51-63.
PMID: 35165894
Objective: Major depressive disorder (MDD) is a highly prevalent condition and a significant contributor to global disability. The vast majority of MDD is handled by primary care, but most real-life...
5.
Kim J, Autry A, Na E, Adachi M, Bjorkholm C, Kavalali E, et al.
Nat Neurosci
. 2021 Jun;
24(8):1100-1109.
PMID: 34183865
The rapidly acting antidepressants ketamine and scopolamine exert behavioral effects that can last from several days to more than a week in some patients. The molecular mechanisms underlying the maintenance...
6.
Titulaer J, Bjorkholm C, Feltmann K, Malmlof T, Mishra D, Bengtsson Gonzales C, et al.
Front Behav Neurosci
. 2021 Apr;
15:667244.
PMID: 33927604
Dopaminergic neurons originating from the ventral tegmental area (VTA) and the locus coeruleus are innervating the ventral hippocampus and are thought to play an essential role for efficient cognitive function....
7.
Bjorkholm C, Marcus M, Konradsson-Geuken A, Jardemark K, Svensson T
Eur Neuropsychopharmacol
. 2017 Feb;
27(4):411-417.
PMID: 28190661
Brexpiprazole (Rexulti), a novel D2/3 receptor (R) partial agonist, was recently approved as monotherapy for schizophrenia, demonstrating effectiveness against both positive and negative symptoms, and also approved as add-on treatment...
8.
Marcus M, Bjorkholm C, Malmerfelt A, Moller A, Pahlsson N, Konradsson-Geuken A, et al.
Eur Neuropsychopharmacol
. 2016 Jul;
26(9):1401-1411.
PMID: 27474687
Nicotine has been found to improve cognition and reduce negative symptoms in schizophrenia and a genetic and pathophysiological link between the α7 nicotinic acetylcholine receptors (nAChRs) and schizophrenia has been...
9.
Bjorkholm C, Monteggia L
Neuropharmacology
. 2015 Nov;
102:72-9.
PMID: 26519901
How do antidepressants elicit an antidepressant response? Here, we review accumulating evidence that the neurotrophin brain-derived neurotrophic factor (BDNF) serves as a transducer, acting as the link between the antidepressant...
10.
Bjorkholm C, Jardemark K, Schilstrom B, Svensson T
Eur Neuropsychopharmacol
. 2015 Aug;
25(10):1842-7.
PMID: 26233606
Preclinical studies indicate that the rapid antidepressant effect of ketamine is dependent on activation of AMPA receptors in the medial prefrontal cortex (mPFC) resulting in a prolonged enhancement of glutamatergic...