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Carine Becamel

Explore the profile of Carine Becamel including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 812
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Recent Articles
1.
Sekssaoui M, Bockaert J, Marin P, Becamel C
Neuropsychopharmacology . 2024 Jan; 49(4):747-756. PMID: 38212441
Major depressive disorder (MDD) is one of the most disabling psychiatric disorders in the world. First-line treatments such as selective serotonin reuptake inhibitors (SSRIs) still have many limitations, including a...
2.
Grychowska K, Lopez-Sanchez U, Vitalis M, Canet G, Satala G, Olejarz-Maciej A, et al.
J Med Chem . 2023 Oct; 66(21):14928-14947. PMID: 37797083
The multifactorial origin and neurochemistry of Alzheimer's disease (AD) call for the development of multitarget treatment strategies. We report a first-in-class triple acting compound that targets serotonin type 6 and...
3.
Berthoux C, Hamieh A, Rogliardo A, Doucet E, Coudert C, Ango F, et al.
EMBO Mol Med . 2022 Sep; 14(9):e16481. PMID: 36069082
No abstract available.
4.
Prouzeau D, Conejero I, Voyvodic P, Becamel C, Abbar M, Lopez-Castroman J
Curr Psychiatry Rep . 2022 Aug; 24(10):573-581. PMID: 35953638
Purpose Of The Review: We aim to provide an overview of the current state of knowledge about the efficacy of psilocybin in the treatment of depression, as well as its...
5.
Veleanu M, Urrieta-Chavez B, Sigoillot S, Paul M, Usardi A, Iyer K, et al.
Proc Natl Acad Sci U S A . 2022 May; 119(21):e2122544119. PMID: 35588456
Environmental perturbations during the first years of life are a major factor in psychiatric diseases. Phencyclidine (PCP), a drug of abuse, has psychomimetic effects, and neonatal subchronic administration of PCP...
6.
Pedzich B, Rubens S, Sekssaoui M, Pierre A, Van Schuerbeek A, Marin P, et al.
Neuropsychopharmacology . 2022 Apr; 47(7):1304-1314. PMID: 35449450
Psychedelic-assisted psychotherapy gained considerable interest as a novel treatment strategy for fear-related mental disorders but the underlying mechanism remains poorly understood. The serotonin 2A (5-HT2A) receptor is a key target...
7.
Doucet E, Grychowska K, Zajdel P, Bockaert J, Marin P, Becamel C
Int J Mol Sci . 2021 Sep; 22(18). PMID: 34576341
Neurofibromatosis type 1 (NF1) is a common inherited disorder caused by mutations of the gene that encodes the Ras-GTPase activating protein neurofibromin, leading to overactivation of Ras-dependent signaling pathways such...
8.
Bockaert J, Becamel C, Chaumont-Dubel S, Claeysen S, Vandermoere F, Marin P
Fac Rev . 2021 Jul; 10:52. PMID: 34195691
Serotonin (5-HT) appeared billions of years before 5-HT receptors and synapses. It is thus not surprising that 5-HT can control biological processes independently of its receptors. One example is serotonylation,...
9.
Barnes N, Ahern G, Becamel C, Bockaert J, Camilleri M, Chaumont-Dubel S, et al.
Pharmacol Rev . 2020 Dec; 73(1):310-520. PMID: 33370241
5-HT receptors expressed throughout the human body are targets for established therapeutics and various drugs in development. Their diversity of structure and function reflects the important role 5-HT receptors play...
10.
Berthoux C, Hamieh A, Rogliardo A, Doucet E, Coudert C, Ango F, et al.
EMBO Mol Med . 2020 Apr; 12(5):e10605. PMID: 32329240
Cannabis abuse during adolescence confers an increased risk for developing later in life cognitive deficits reminiscent of those observed in schizophrenia, suggesting common pathological mechanisms that remain poorly characterized. In...