Carina Trummer
Overview
Explore the profile of Carina Trummer including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
134
Followers
0
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Recent Articles
1.
Lorenzl S, Gottwald F, Nistler A, Brehm L, Grotsch R, Haber G, et al.
Med Cannabis Cannabinoids
. 2022 Feb;
5(1):9-19.
PMID: 35224436
Introduction: A phase I, open-label clinical trial in healthy male subjects was conducted to assess the pharmacokinetic and safety profile of an oromucosal cannabinoid spray (AP701) containing a lipid-based nanoparticular...
2.
Mulholland C, Nishiyama A, Ryan J, Nakamura R, Yigit M, Gluck I, et al.
Nat Commun
. 2020 Dec;
11(1):6443.
PMID: 33335103
No abstract available.
3.
Mulholland C, Nishiyama A, Ryan J, Nakamura R, Yigit M, Gluck I, et al.
Nat Commun
. 2020 Nov;
11(1):5972.
PMID: 33235224
Genome-wide DNA demethylation is a unique feature of mammalian development and naïve pluripotent stem cells. Here, we describe a recently evolved pathway in which global hypomethylation is achieved by the...
4.
Nishiyama A, Mulholland C, Bultmann S, Kori S, Endo A, Saeki Y, et al.
Nat Commun
. 2020 Mar;
11(1):1222.
PMID: 32144273
Stable inheritance of DNA methylation is critical for maintaining differentiated phenotypes in multicellular organisms. We have recently identified dual mono-ubiquitylation of histone H3 (H3Ub2) by UHRF1 as an essential mechanism...
5.
Schneider M, Trummer C, Stengl A, Zhang P, Szwagierczak A, Cardoso M, et al.
PLoS One
. 2020 Feb;
15(2):e0229144.
PMID: 32084194
The multi-domain protein UHRF1 is essential for DNA methylation maintenance and binds DNA via a base-flipping mechanism with a preference for hemi-methylated CpG sites. We investigated its binding to hemi-...
6.
Ludwig A, Zhang P, Hastert F, Meyer S, Rausch C, Herce H, et al.
Nucleic Acids Res
. 2016 Dec;
45(5):2438-2457.
PMID: 27923996
Aberrant DNA methylation is a hallmark of various human disorders, indicating that the spatial and temporal regulation of methylation readers and modifiers is imperative for development and differentiation. In particular,...