Canrong Wu
Overview
Explore the profile of Canrong Wu including associated specialties, affiliations and a list of published articles.
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26
Citations
1629
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Recent Articles
1.
Xu J, Xu Y, Hou L, He X, Li Y, Zhao J, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
121(51):e2403304121.
PMID: 39665758
Prostaglandin D2 receptor 2 (DP2) is an important anti-inflammatory and antiallergic drug target. While inactive DP2 structures are known, its activation mechanisms and biased signaling remain unclear. Here, we report...
2.
Li Y, Yuan Q, He X, Zhang Y, You C, Wu C, et al.
Cell Discov
. 2024 Sep;
10(1):91.
PMID: 39223120
Prolactin-releasing peptide (PrRP) is an RF-amide neuropeptide that binds and activates its cognate G protein-coupled receptor, prolactin-releasing peptide receptor (PrRPR), also known as GPR10. PrRP and PrRPR are highly conserved...
3.
Jin S, Guo S, Xu Y, Li X, Wu C, He X, et al.
Cell Discov
. 2024 Jun;
10(1):58.
PMID: 38830850
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis,...
4.
Zhang H, Yin Y, Dai A, Zhang T, Zhang C, Wu C, et al.
Nature
. 2024 May;
630(8015):247-254.
PMID: 38750358
The noradrenaline transporter has a pivotal role in regulating neurotransmitter balance and is crucial for normal physiology and neurobiology. Dysfunction of noradrenaline transporter has been implicated in numerous neuropsychiatric diseases,...
5.
He Q, Yuan Q, Shan H, Wu C, Gu Y, Wu K, et al.
Cell Discov
. 2024 May;
10(1):48.
PMID: 38710677
Melanin-concentrating hormone (MCH) is a cyclic neuropeptide that regulates food intake, energy balance, and other physiological functions by stimulating MCHR1 and MCHR2 receptors, both of which are class A G...
6.
Wang J, Jin S, Zhang H, Xu Y, Hu W, Jiang Y, et al.
Sci Adv
. 2024 Feb;
10(6):eadk5184.
PMID: 38335293
The prostacyclin (PGI) receptor (IP) is a G-coupled receptor associated with blood pressure regulation, allergy, and inflammatory response. It is a main therapeutic target for pulmonary arterial hypertension (PAH) and...
7.
Wu C, Xu Y, He Q, Li D, Duan J, Li C, et al.
Nat Commun
. 2023 May;
14(1):2668.
PMID: 37160891
Prostaglandin F (PGF), an endogenous arachidonic acid metabolite, regulates diverse physiological functions in many tissues and cell types through binding and activation of a G-protein-coupled receptor (GPCR), the PGF receptor...
8.
Jin S, Wu C, Chen M, Sun D, Zhang H
Front Med (Lausanne)
. 2022 Aug;
9:923334.
PMID: 35966876
Mesenchymal stem cells (MSCs) have made progress in the treatment of ischemic and inflammatory diseases. Preeclampsia (PE) is characterized by placenta ischemic and inflammatory injury. Our paper summarized the new...
9.
Xu Y, Wu C, Cao X, Gu C, Liu H, Jiang M, et al.
Cell Res
. 2022 May;
32(7):609-620.
PMID: 35641567
The Omicron BA.2 variant has become a dominant infective strain worldwide. Receptor binding studies show that the Omicron BA.2 spike trimer exhibits 11-fold and 2-fold higher potency in binding to...
10.
Yin W, Xu Y, Xu P, Cao X, Wu C, Gu C, et al.
Science
. 2022 Feb;
375(6584):1048-1053.
PMID: 35133176
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has become the dominant infective strain. We report the structures of the Omicron spike trimer on its own and in...