Candice L Brinkmeyer-Langford
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Explore the profile of Candice L Brinkmeyer-Langford including associated specialties, affiliations and a list of published articles.
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13
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717
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Recent Articles
1.
Perez Gomez A, Wang M, Kochan K, Amstalden K, Young C, Welsh C, et al.
Front Immunol
. 2023 Aug;
14:1228509.
PMID: 37600798
Introduction: Neurological diseases can stem from environmental influences such as antecedent viral infections or exposure to potential toxicants, some of which can trigger immune responses leading to neurological symptoms. Theiler's...
2.
Lawley K, Rech R, Perez Gomez A, Hopkins L, Han G, Amstalden K, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142395
A wide range of viruses cause neurological manifestations in their hosts. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional...
3.
Lawley K, Rech R, Elenwa F, Han G, Perez Gomez A, Amstalden K, et al.
PLoS One
. 2021 Aug;
16(8):e0256370.
PMID: 34415947
Host genetic background is a significant driver of the variability in neurological responses to viral infection. Here, we leverage the genetically diverse Collaborative Cross (CC) mouse resource to better understand...
4.
Brinkmeyer-Langford C, Rech R, Amstalden K, Kochan K, Hillhouse A, Young C, et al.
Sci Rep
. 2017 Sep;
7(1):12194.
PMID: 28939838
Infection by Theiler's murine encephalomyelitis virus (TMEV) is a model for neurological outcomes caused by virus infection because it leads to diverse neurological conditions in mice, depending on the strain...
5.
Markham L, Brinkmeyer-Langford C, Soslow J, Gupte M, Sawyer D, Kornegay J, et al.
BMC Med Genomics
. 2017 Apr;
10(1):21.
PMID: 28390424
Background: Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene, which codes for the dystrophin protein. While progress has been made in defining the molecular basis and...
6.
Brinkmeyer-Langford C, Guan J, Ji G, Cai J
Front Aging Neurosci
. 2016 Aug;
8:183.
PMID: 27536236
Human aging is associated with cognitive decline and an increased risk of neurodegenerative disease. Our objective for this study was to evaluate potential relationships between age and variation in gene...
7.
Galindo C, Soslow J, Brinkmeyer-Langford C, Gupte M, Smith H, Sengsayadeth S, et al.
Pediatr Res
. 2015 Dec;
79(4):629-36.
PMID: 26672735
Background: In Duchenne muscular dystrophy (DMD), abnormal cardiac function is typically preceded by a decade of skeletal muscle disease. Molecular reasons for differences in onset and progression of these muscle...
8.
Zeng Y, Wang G, Yang E, Ji G, Brinkmeyer-Langford C, Cai J
PLoS Genet
. 2015 Jan;
11(1):e1004942.
PMID: 25617623
Gene expression as an intermediate molecular phenotype has been a focus of research interest. In particular, studies of expression quantitative trait loci (eQTL) have offered promise for understanding gene regulation...
9.
Kornegay J, Spurney C, Nghiem P, Brinkmeyer-Langford C, Hoffman E, Nagaraju K
ILAR J
. 2014 Jun;
55(1):119-49.
PMID: 24936034
Duchenne muscular dystrophy (DMD) is an X-linked human disorder in which absence of the protein dystrophin causes degeneration of skeletal and cardiac muscle. For the sake of treatment development, over...
10.
Wang G, Yang E, Mandhan I, Brinkmeyer-Langford C, Cai J
Eur J Hum Genet
. 2014 Jan;
22(9):1093-9.
PMID: 24398800
Human mitochondria contain multiple copies of a circular genome made up of double-stranded DNA (mtDNA) that encodes proteins involved in cellular respiration. Transcript abundance of mtDNA-encoded genes varies between human...