Candace Guiducci
Overview
Explore the profile of Candace Guiducci including associated specialties, affiliations and a list of published articles.
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55
Citations
22757
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Recent Articles
1.
Lennon N, Kottyan L, Kachulis C, Abul-Husn N, Arias J, Belbin G, et al.
medRxiv
. 2023 Jun;
PMID: 37333246
Polygenic risk scores (PRS) have improved in predictive performance supporting their use in clinical practice. Reduced predictive performance of PRS in diverse populations can exacerbate existing health disparities. The NHGRI-funded...
2.
Linder J, Allworth A, Bland H, Caraballo P, Chisholm R, Clayton E, et al.
Genet Med
. 2023 Jan;
25(4):100006.
PMID: 36621880
Purpose: Assessing the risk of common, complex diseases requires consideration of clinical risk factors as well as monogenic and polygenic risks, which in turn may be reflected in family history....
3.
Ford C, Funt J, Abbey D, Issi L, Guiducci C, Martinez D, et al.
Elife
. 2015 Feb;
4:e00662.
PMID: 25646566
Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading...
4.
Mahajan A, Go M, Zhang W, Below J, Gaulton K, Ferreira T, et al.
Nat Genet
. 2014 Feb;
46(3):234-44.
PMID: 24509480
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European,...
5.
Billings L, Jablonski K, Ackerman R, Taylor A, Fanelli R, McAteer J, et al.
J Clin Endocrinol Metab
. 2014 Jan;
99(5):E926-30.
PMID: 24471563
Context/objective: The variant rs13266634 in SLC30A8, encoding a β-cell-specific zinc transporter, is associated with type 2 diabetes. We aimed to identify other variants in SLC30A8 that increase diabetes risk and...
6.
Baca S, Prandi D, Lawrence M, Mosquera J, Romanel A, Drier Y, et al.
Cell
. 2013 Apr;
153(3):666-77.
PMID: 23622249
The analysis of exonic DNA from prostate cancers has identified recurrently mutated genes, but the spectrum of genome-wide alterations has not been profiled extensively in this disease. We sequenced the...
7.
Dulak A, Stojanov P, Peng S, Lawrence M, Fox C, Stewart C, et al.
Nat Genet
. 2013 Mar;
45(5):478-86.
PMID: 23525077
The incidence of esophageal adenocarcinoma (EAC) has risen 600% over the last 30 years. With a 5-year survival rate of ~15%, the identification of new therapeutic targets for EAC is...
8.
Diogo D, Kurreeman F, Stahl E, Liao K, Gupta N, Greenberg J, et al.
Am J Hum Genet
. 2012 Dec;
92(1):15-27.
PMID: 23261300
The extent to which variants in the protein-coding sequence of genes contribute to risk of rheumatoid arthritis (RA) is unknown. In this study, we addressed this issue by deep exon...
9.
Sandholm N, Salem R, McKnight A, Brennan E, Forsblom C, Isakova T, et al.
PLoS Genet
. 2012 Oct;
8(9):e1002921.
PMID: 23028342
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation. In...
10.
Grant R, OBrien K, Waxler J, Vassy J, Delahanty L, Bissett L, et al.
Diabetes Care
. 2012 Aug;
36(1):13-9.
PMID: 22933432
Objective: To examine whether diabetes genetic risk testing and counseling can improve diabetes prevention behaviors. Research Design And Methods: We conducted a randomized trial of diabetes genetic risk counseling among...