Can Can Xue
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Explore the profile of Can Can Xue including associated specialties, affiliations and a list of published articles.
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15
Citations
29
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Recent Articles
1.
Sim M, Tham Y, Nusinovici S, Quek T, Yu M, Xue C, et al.
Alzheimers Dement
. 2025 Mar;
21(3):e14601.
PMID: 40042460
Introduction: The utility of retinal photography-derived aging biomarkers for predicting cognitive decline remains under-explored. Methods: A memory-clinic cohort in Singapore was followed-up for 5 years. RetiPhenoAge, a retinal aging biomarker,...
2.
Pan Z, Li Z, Xie H, Huang Y, Xue C, Wu X, et al.
Graefes Arch Clin Exp Ophthalmol
. 2025 Feb;
PMID: 40009225
Purpose: To investigate the relationship between retinal layer thickness and cognitive function in elderly Chinese, accounting for the influence of axial length. Methods: The participants of the Beijing Eye Study...
3.
Yew S, Lei X, Chen Y, Goh J, Pushpanathan K, Xue C, et al.
Ophthalmol Sci
. 2025 Feb;
5(2):100659.
PMID: 39931359
Purpose: Recent studies utilized ocular images and deep learning (DL) to predict refractive error and yielded notable results. However, most studies did not address biases from imbalanced datasets or conduct...
4.
Chen H, Jiang Z, Liu X, Xue C, Yew S, Sheng B, et al.
Br J Ophthalmol
. 2025 Jan;
PMID: 39814458
Background/aims: Large language models (LLMs) have substantial potential to enhance the efficiency of academic research. The accuracy and performance of LLMs in a systematic review, a core part of evidence...
5.
Xue C, Nusinovici S, Yu M, Chee M, Teo K, Su X, et al.
Eye (Lond)
. 2024 Dec;
PMID: 39719503
Objectives: To determine the association between telomere length (TL) and age-related macular degeneration (AMD) and examine the potential variations with sex and ethnicity. Methods: Population-based, cross-sectional study. A total of...
6.
Xue C, Li H, Yu M, Chong C, Fan Q, Tham Y, et al.
Ophthalmology
. 2024 Dec;
PMID: 39662686
Purpose: Epidemiologic studies and clinical trials have reported inconsistent findings regarding omega-3 fatty acids' protective role in age-related macular degeneration (AMD). We investigated their association in a prospective cohort and...
7.
Cui Y, Cui J, Xue C, Mao Y, Jonas J, Wang Y, et al.
Transl Vis Sci Technol
. 2024 Dec;
13(12):10.
PMID: 39641966
Purpose: To examine the 5-year incidence of age-related macular degeneration (AMD) and its associated factors in an adult Chinese population. Methods: The Tongren Health Care Study included individuals attending regular...
8.
Xue C, Teo K, Tham Y, Li H, Thakur S, Sabanayagam C, et al.
iScience
. 2024 Dec;
27(12):111344.
PMID: 39640589
We investigated whether the effect of lipid-lowering drugs (LLDs) on age-related macular degeneration (AMD) differs according to the main complement genetic variants in Singapore Epidemiology of Eye Diseases (SEED) ( ...
9.
Nusinovici S, Rim T, Li H, Yu M, Deshmukh M, Quek T, et al.
Lancet Healthy Longev
. 2024 Oct;
5(10):100593.
PMID: 39362226
Background: Biological ageing markers are useful to risk stratify morbidity and mortality more precisely than chronological age. In this study, we aimed to develop a novel deep-learning-based biological ageing marker...
10.
Xue C, Li H, Dong X, Yu M, Soh Z, Chong C, et al.
Am J Ophthalmol
. 2024 Sep;
268:368-377.
PMID: 39244001
Purpose: Animal models suggest omega-3 polyunsaturated fatty acids (PUFAs) may protect against myopia by modulating choroidal blood perfusion, but clinical evidence is scarce and mixed. We aimed to determine the...