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Camille Bonomelli

Explore the profile of Camille Bonomelli including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 831
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Recent Articles
1.
Vasiljevic S, Beale E, Bonomelli C, Easthope I, Pritchard L, Seabright G, et al.
Mol Immunol . 2015 Sep; 68(2 Pt A):234-43. PMID: 26391350
Effective use of adenovirus-5 (Ad5) in cancer therapy is heavily dependent on the degree to which the virus's natural tropism can be subverted to one that favours tumour cells. This...
2.
Harvey D, Crispin M, Bonomelli C, Scrivens J
J Am Soc Mass Spectrom . 2015 Jul; 26(10):1754-67. PMID: 26204966
Many samples of complex mixtures of N-glycans released from small amounts of material, such as glycoproteins from viruses, present problems for mass spectrometric analysis because of the presence of contaminating...
3.
Pritchard L, Spencer D, Royle L, Bonomelli C, Seabright G, Behrens A, et al.
Nat Commun . 2015 Jun; 6:7479. PMID: 26105115
The envelope spike of HIV-1 employs a 'glycan shield' to protect itself from antibody-mediated neutralization. Paradoxically, however, potent broadly neutralizing antibodies (bnAbs) that target this shield have been isolated. The...
4.
Pritchard L, Harvey D, Bonomelli C, Crispin M, Doores K
J Virol . 2015 Jun; 89(17):8932-44. PMID: 26085151
Unlabelled: The gp120/gp41 HIV-1 envelope glycoprotein (Env) is highly glycosylated, with up to 50% of its mass consisting of N-linked glycans. This dense carbohydrate coat has emerged as a promising...
5.
Harvey D, Edgeworth M, Krishna B, Bonomelli C, Allman S, Crispin M, et al.
Rapid Commun Mass Spectrom . 2014 Aug; 28(18):2008-18. PMID: 25132301
Rationale: Negative ion collision-induced dissociation (CID) spectra of N-glycans contain many diagnostic ions that provide more structural information than positive ion spectra. EndoH or endoS release of glycans from glycoproteins,...
6.
Crispin M, Harvey D, Bitto D, Halldorsson S, Bonomelli C, Edgeworth M, et al.
J Virol . 2014 Jun; 88(17):10244-51. PMID: 24942574
Uukuniemi virus (UUKV) is a model system for investigating the genus Phlebovirus of the Bunyaviridae. We report the UUKV glycome, revealing differential processing of the Gn and Gc virion glycoproteins....
7.
Crispin M, Harvey D, Bitto D, Bonomelli C, Edgeworth M, Scrivens J, et al.
J Proteome Res . 2014 Jan; 13(3):1702-12. PMID: 24467287
Cross-species viral transmission subjects parent and progeny alphaviruses to differential post-translational processing of viral envelope glycoproteins. Alphavirus biogenesis has been extensively studied, and the Semliki Forest virus E1 and E2...
8.
Harvey D, Scarff C, Crispin M, Scanlan C, Bonomelli C, Scrivens J
J Am Soc Mass Spectrom . 2012 Sep; 23(11):1955-66. PMID: 22993039
The preference for singly charged ion formation by MALDI makes it a better choice than electrospray ionization for profiling mixtures of N-glycans. For structural analysis, fragmentation of negative ions often...
9.
Goodfellow J, Baruah K, Yamamoto K, Bonomelli C, Krishna B, Harvey D, et al.
J Am Chem Soc . 2012 May; 134(19):8030-3. PMID: 22551167
Protein endoglycosidases are useful for biocatalytic alteration of glycans on protein surfaces, but the currently limited selectivity of endoglycosidases has prevented effective manipulation of certain N-linked glycans widely found in...
10.
Bonomelli C, Doores K, Dunlop D, Thaney V, Dwek R, Burton D, et al.
PLoS One . 2011 Aug; 6(8):e23521. PMID: 21858152
The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration...