Calvin B Williams
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Explore the profile of Calvin B Williams including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Sabbagh S, Haribhai D, Gershan J, Verbsky J, Nocton J, Yassai M, et al.
Front Immunol
. 2024 Jul;
15:1446946.
PMID: 38962010
[This corrects the article DOI: 10.3389/fimmu.2024.1306490.].
2.
Sabbagh S, Haribhai D, Gershan J, Verbsky J, Nocton J, Yassai M, et al.
Front Immunol
. 2024 Jun;
15:1306490.
PMID: 38873594
Recurrent exposures to a pathogenic antigen remodel the CD8 T cell compartment and generate a functional memory repertoire that is polyclonal and complex. At the clonotype level, the response to...
3.
Khatun A, Wu X, Qi F, Gai K, Kharel A, Kudek M, et al.
Adv Sci (Weinh)
. 2023 Aug;
10(28):e2206692.
PMID: 37587835
Regulatory T (Treg) cells are inevitable to prevent deleterious immune responses to self and commensal microorganisms. Treg function requires continuous expression of the transcription factor (TF) FOXP3 and is divided...
4.
Cai Y, Schroeder J, Jing W, Gurski C, Williams C, Wang S, et al.
Front Immunol
. 2022 Nov;
13:1029356.
PMID: 36389708
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system with no cure yet. Here, we report genetic engineering of hematopoietic stem cells (HSCs) to express...
5.
Li J, Chen J, Schroeder J, Hu J, Williams C, Shi Q
Mol Ther Nucleic Acids
. 2021 Feb;
23:719-730.
PMID: 33575117
While platelet-specific gene therapy is effective in inducing immune tolerance to a targeted protein, how the reactivity of pre-existing immunity affects the efficacy, and whether CD8 T cells were involved...
6.
Zheng Y, Zhu W, Haribhai D, Williams C, Aster R, Wen R, et al.
J Immunol
. 2019 Sep;
203(7):1786-1792.
PMID: 31471526
Heparin-induced thrombocytopenia is a relatively common drug-induced immune disorder that can have life-threatening consequences for affected patients. Immune complexes consisting of heparin, platelet factor 4 (PF4), and PF4/heparin-reactive Abs are...
7.
Naumova E, Yassai M, Demos W, Reed E, Unruh M, Haribhai D, et al.
Front Immunol
. 2019 Aug;
10:1717.
PMID: 31447830
T-cell memory to pathogens can be envisioned as a receptor-based imprint of the pathogenic environment on the naïve repertoire of clonotypes. Recurrent exposures to a pathogen inform and reinforce memory,...
8.
Owen D, Mahmud S, Sjaastad L, Williams J, Spanier J, Simeonov D, et al.
Nat Immunol
. 2019 Jan;
20(2):195-205.
PMID: 30643267
The developmental programs that generate a broad repertoire of regulatory T cells (T cells) able to respond to both self antigens and non-self antigens remain unclear. Here we found that...
9.
Luo X, Chen J, Schroeder J, Allen K, Baumgartner C, Malarkannan S, et al.
Front Immunol
. 2018 Sep;
9:1950.
PMID: 30237796
Delivery of gene therapy as well as of biologic therapeutics is often hampered by the immune response of the subject receiving the therapy. We have reported that effective gene therapy...
10.
Hinze C, Foell D, Johnson A, Spalding S, Gottlieb B, Morris P, et al.
Arthritis Rheumatol
. 2018 Sep;
71(3):451-459.
PMID: 30225949
Objective: To determine the relationship between serum levels of S100A8/A9 and S100A12 and the maintenance of clinically inactive disease during anti-tumor necrosis factor (anti-TNF) therapy and the occurrence of disease...