Caleigh Mandel-Brehm
Overview
Explore the profile of Caleigh Mandel-Brehm including associated specialties, affiliations and a list of published articles.
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25
Citations
1171
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Recent Articles
1.
Bodansky A, Mettelman R, Sabatino Jr J, Vazquez S, Chou J, Novak T, et al.
Nature
. 2024 Aug;
632(8025):622-629.
PMID: 39112696
Multisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela of SARS-CoV-2 infection, yet the pathophysiological mechanism connecting the infection to the broad inflammatory syndrome remains unknown. Here we...
2.
Bodansky A, Yu D, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green D, et al.
J Clin Invest
. 2024 May;
134(13).
PMID: 38753445
Given the global surge in autoimmune diseases, it is critical to evaluate emerging therapeutic interventions. Despite numerous new targeted immunomodulatory therapies, comprehensive approaches to apply and evaluate the effects of...
3.
Bodansky A, Yu D, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green D, et al.
medRxiv
. 2024 Jan;
PMID: 38196603
The prevalence and burden of autoimmune and autoantibody mediated disease is increasing worldwide, yet most disease etiologies remain unclear. Despite numerous new targeted immunomodulatory therapies, comprehensive approaches to apply and...
4.
Rackaityte E, Proekt I, Miller H, Ramesh A, Brooks J, Kung A, et al.
JCI Insight
. 2023 Nov;
8(23).
PMID: 37934865
Autoimmunity is characterized by loss of tolerance to tissue-specific as well as systemic antigens, resulting in complex autoantibody landscapes. Here, we introduce and extensively validate the performance characteristics of a...
5.
Rackaityte E, Proekt I, Miller H, Ramesh A, Brooks J, Kung A, et al.
bioRxiv
. 2023 Apr;
PMID: 37066405
Autoimmunity is characterized by loss of tolerance to tissue-specific as well as systemic antigens, resulting in complex autoantibody landscapes. Here, we introduce and extensively validate the performance characteristics of a...
6.
Vazquez S, Mann S, Bodansky A, Kung A, Quandt Z, Ferre E, et al.
Elife
. 2022 Oct;
11.
PMID: 36300623
Phage immunoprecipitation sequencing (PhIP-seq) allows for unbiased, proteome-wide autoantibody discovery across a variety of disease settings, with identification of disease-specific autoantigens providing new insight into previously poorly understood forms of...
7.
Mandel-Brehm C, Vazquez S, Liverman C, Cheng M, Quandt Z, Kung A, et al.
Diabetes
. 2022 Jun;
72(1):59-70.
PMID: 35709010
Acquired lipodystrophy is often characterized as an idiopathic subtype of lipodystrophy. Despite suspicion of an immune-mediated pathology, biomarkers such as autoantibodies are generally lacking. Here, we used an unbiased proteome-wide...
8.
Mandel-Brehm C, Benson L, Tran B, Kung A, Mann S, Vazquez S, et al.
Ann Neurol
. 2022 Apr;
92(2):279-291.
PMID: 35466441
Objective: Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD), is a severe pediatric disorder of uncertain etiology resulting in hypothalamic dysfunction and frequent sudden death. Frequent co-occurrence of...
9.
Vazquez S, Mann S, Bodansky A, Kung A, Quandt Z, Ferre E, et al.
bioRxiv
. 2022 Mar;
PMID: 35350199
Phage Immunoprecipitation-Sequencing (PhIP-Seq) allows for unbiased, proteome-wide autoantibody discovery across a variety of disease settings, with identification of disease-specific autoantigens providing new insight into previously poorly understood forms of immune...
10.
Ishikawa H, Mandel-Brehm C, Shindo A, Cady M, Mann S, Niwa A, et al.
Eur J Neurol
. 2021 Sep;
28(12):4261-4266.
PMID: 34561925
Background And Purpose: The aim of this study was to identify the long-term radiological changes, autoantibody specificities, and clinical course in a patient with kelch-like protein 11 (KLHL11)-associated paraneoplastic neurological...