Caleb J Kennedy
Overview
Explore the profile of Caleb J Kennedy including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
796
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0
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Recent Articles
1.
Raoof S, Kennedy C, Wallach D, Bitton A, Green R
Nat Med
. 2021 Jul;
27(7):1139-1142.
PMID: 34211183
No abstract available.
2.
Lyng G, Sheils N, Kennedy C, Griffin D, Berke E
PLoS One
. 2021 Mar;
16(3):e0248783.
PMID: 33764982
Background: COVID-19 test sensitivity and specificity have been widely examined and discussed, yet optimal use of these tests will depend on the goals of testing, the population or setting, and...
3.
Wang W, Huang H, Halagan M, Vierra-Green C, Heuer M, Brelsford J, et al.
Blood Adv
. 2018 Sep;
2(19):2419-2429.
PMID: 30262602
Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a curative option for blood cancers, but the coupled effects of graft-versus-tumor and graft-versus-host disease (GVHD) limit its broader application. Outcomes improve with...
4.
Milius R, Heuer M, Valiga D, Doroschak K, Kennedy C, Bolon Y, et al.
Hum Immunol
. 2015 Aug;
76(12):963-74.
PMID: 26319908
We present an electronic format for exchanging data for HLA and KIR genotyping with extensions for next-generation sequencing (NGS). This format addresses NGS data exchange by refining the Histoimmunogenetics Markup...
5.
Perreault-Micale C, Frieden A, Kennedy C, Neitzel D, Sullivan J, Faulkner N, et al.
J Mol Diagn
. 2014 Oct;
16(6):673-8.
PMID: 25307757
Loss of function variants in the PCDH15 gene can cause Usher syndrome type 1F, an autosomal recessive disease associated with profound congenital hearing loss, vestibular dysfunction, and retinitis pigmentosa. The...
6.
Hallam S, Nelson H, Greger V, Perreault-Micale C, Davie J, Faulkner N, et al.
J Mol Diagn
. 2013 Dec;
16(2):180-9.
PMID: 24374108
Traditional carrier screening assays are designed to look for only the most common mutations within a gene owing to cost considerations. Although this can yield high detection rates in specific...
7.
Umbarger M, Kennedy C, Saunders P, Breton B, Chennagiri N, Emhoff J, et al.
Genet Med
. 2013 Jun;
16(2):132-40.
PMID: 23765052
Purpose: Carrier screening for recessive Mendelian disorders traditionally employs focused genotyping to interrogate limited sets of mutations most prevalent in specific ethnic groups. We sought to develop a next-generation DNA...
8.
Senapedis W, Kennedy C, Boyle P, Silver P
Mol Biol Cell
. 2011 Apr;
22(10):1791-805.
PMID: 21460183
Forkhead transcription factors (FOXOs) alter a diverse array of cellular processes including the cell cycle, oxidative stress resistance, and aging. Insulin/Akt activation directs phosphorylation and cytoplasmic sequestration of FOXO away...
9.
Moore M, Wang Q, Kennedy C, Silver P
Cell
. 2010 Aug;
142(4):625-36.
PMID: 20705336
Alternative splicing is a vast source of biological regulation and diversity that is misregulated in cancer and other diseases. To investigate global control of alternative splicing in human cells, we...
10.
Birmingham A, Selfors L, Forster T, Wrobel D, Kennedy C, Shanks E, et al.
Nat Methods
. 2009 Aug;
6(8):569-75.
PMID: 19644458
RNA interference (RNAi) has become a powerful technique for reverse genetics and drug discovery, and in both of these areas large-scale high-throughput RNAi screens are commonly performed. The statistical techniques...