Caitriona OConnor
Overview
Explore the profile of Caitriona OConnor including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
150
Followers
0
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Recent Articles
1.
Silk J, Abbott R, Adams K, Bennett A, Brett S, Cornforth T, et al.
J Immunol
. 2021 Dec;
208(1):169-180.
PMID: 34853077
Adoptive T cell therapy with T cells expressing affinity-enhanced TCRs has shown promising results in phase 1/2 clinical trials for solid and hematological tumors. However, depth and durability of responses...
2.
Chaudhury S, OConnor C, Canete A, Bittencourt-Silvestre J, Sarrou E, Prendergast A, et al.
Nat Commun
. 2018 Dec;
9(1):5280.
PMID: 30538250
Acute myeloid leukaemia (AML) affects children and adults of all ages. AML remains one of the major causes of death in children with cancer and for children with AML relapse...
3.
OConnor C, Yalla K, Salome M, Moka H, Castaneda E, Eyers P, et al.
Oncotarget
. 2018 Mar;
9(19):14977-14992.
PMID: 29599919
Trib2 pseudokinase has oncogenic and tumour suppressive functions depending on the cellular context. We investigated the ability of Trib2 to transform different haemopoietic stem and progenitor cells (HSPCs). Our study...
4.
Liang K, OConnor C, Veiga J, McCarthy T, Keeshan K
Cell Discov
. 2016 Jul;
2:15050.
PMID: 27462446
TRIB2, a serine/threonine pseudokinase identified as an oncogene, is expressed at high levels in the T-cell compartment of hematopoiesis. The proliferation of developing thymocytes is tightly controlled to prevent leukemic...
5.
OConnor C, Campos J, Osinski J, Gronostajski R, Michie A, Keeshan K
PLoS One
. 2015 Mar;
10(3):e0120102.
PMID: 25780920
The commitment of stem and progenitor cells toward specific hematopoietic lineages is tightly controlled by a number of transcription factors that regulate differentiation programs via the expression of lineage restricting...
6.
Rishi L, Hannon M, Salome M, Hasemann M, Frank A, Campos J, et al.
Blood
. 2014 Feb;
123(15):2389-400.
PMID: 24516045
The loss of regulation of cell proliferation is a key event in leukemic transformation, and the oncogene tribbles (Trib)2 is emerging as a pivotal target of transcription factors in acute...
7.
Ryan S, OKeeffe G, OConnor C, Keeshan K, Nolan Y
Brain Behav Immun
. 2013 Mar;
33:7-13.
PMID: 23510989
Adult hippocampal neurogenesis is modulated by a number of intrinsic and extrinsic factors including local signalling molecules, exercise, aging and inflammation. Inflammation is also a major contributor to several hippocampal-associated...
8.
Hearty A, Duffy E, Joyce J, OConnor C, Gibney M
Public Health Nutr
. 2008 Mar;
12(1):51-8.
PMID: 18312704
Objective: To study patterns of phytosterol intakes in the Irish population from enriched sources. Design: An interview-assisted questionnaire, which recorded information on sociodemographics, product types, intake amounts and patterns of...