Caitlin S Pepperell
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Explore the profile of Caitlin S Pepperell including associated specialties, affiliations and a list of published articles.
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38
Citations
632
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Recent Articles
1.
Dominguez E, McDonald B, Zhang H, Stephens M, Dietmann E, Nedden M, et al.
Clin Chem
. 2025 Mar;
PMID: 40067770
Background: Diagnosis of sepsis and timely identification of pathogens in critically ill patients remains challenging. Plasma metagenomic sequencing to detect microbial cell-free DNA (mDNA) has shown promise, but low abundance...
2.
Garcia E, Klimowicz A, Edupuganti L, Topf M, Bhide S, Slusser D, et al.
mSphere
. 2024 Jun;
9(7):e0045024.
PMID: 38926904
The genus, comprising at least 13 species, is associated with the polymicrobial disorder bacterial vaginosis (BV). However, the details of BV pathogenesis are poorly defined, and the contributions made by...
3.
Youngblom M, Smith T, Murray H, Pepperell C
PLoS Pathog
. 2024 Apr;
20(4):e1012124.
PMID: 38635841
Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is a leading global cause of death from infectious disease. Biofilms are increasingly recognized as a relevant growth form during...
4.
Youngblom M, Imhoff M, Smyth L, Mohamed M, Pepperell C
bioRxiv
. 2023 Aug;
PMID: 37645846
Data Summary: Raw sequencing data for newly sequenced isolates have been deposited to the NCBI SRA under the project accession PRJNA928770. A list of all genomes used in this work...
5.
Youngblom M, Smith T, Pepperell C
bioRxiv
. 2023 Jul;
PMID: 37503306
Importance: Understanding mechanisms of resistance and tolerance in ( ) can help us develop new treatments that capitalize on 's vulnerabilities. Here we used transcriptomics to study both the regulation...
6.
Bramble J, Pepperell C
J Infect Dis
. 2023 Jul;
228(5):501-502.
PMID: 37440472
No abstract available.
7.
Olaitan A, Dureja C, Youngblom M, Topf M, Shen W, Gonzales-Luna A, et al.
Nat Commun
. 2023 Jul;
14(1):4130.
PMID: 37438331
Severe outbreaks and deaths have been linked to the emergence and global spread of fluoroquinolone-resistant Clostridioides difficile over the past two decades. At the same time, metronidazole, a nitro-containing antibiotic,...
8.
Youngblom M, Shockey A, Callaghan M, Dillard J, Pepperell C
Microb Genom
. 2023 May;
9(5).
PMID: 37213168
The incidence of gonorrhoea is increasing at an alarming pace, and therapeutic options continue to narrow as a result of worsening drug resistance. is naturally competent, allowing the organism to...
9.
Youngblom M, Pepperell C
Cell
. 2022 Nov;
185(24):4467-4469.
PMID: 36423577
In this issue of Cell, Saelens et al. describe a new function for mycobacterial Type VII secretion systems: manipulation of host cell migration. They find that a substantial proportion of...
10.
Joyce L, Youngblom M, Cormaty H, Gartstein E, Barber K, Akins R, et al.
mSphere
. 2022 Nov;
7(6):e0050922.
PMID: 36321824
The viridans group streptococci (VGS) are a large consortium of commensal streptococci that colonize the human body. Many species within this group are opportunistic pathogens causing bacteremia and infective endocarditis...