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Caio Bezerra Machado

Explore the profile of Caio Bezerra Machado including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 49
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Recent Articles
1.
DE Morais G, Machado C, Dias Nogueira B, DE Pinho Pessoa F, DE Sousa Oliveira D, Ribeiro R, et al.
Cancer Diagn Progn . 2024 Sep; 4(5):592-598. PMID: 39238631
Background/aim: Although the reciprocal translocation t(9;22)(q34;q11) is a hallmark of chronic myeloid leukemia (CML), it is also present in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Depending on...
2.
DE Pinho Pessoa F, Dias Nogueira B, Machado C, Barreto I, DA Costa Machado A, Gadelha R, et al.
In Vivo . 2024 Jun; 38(4):2016-2023. PMID: 38936913
Background/aim: Acute myeloid leukemia (AML) is a myeloproliferative neoplasm marked by abnormal clonal expansion of hematopoietic progenitor cells, displaying karyotypic aberrations and genetic mutations as prognostic indicators. The World Health...
3.
DE Pinho Pessoa F, DE Sousa Oliveira D, Dias Nogueira B, DE Albuquerque K, Silva F, Gurgel L, et al.
Anticancer Res . 2024 May; 44(6):2747-2753. PMID: 38821591
Background/aim: The relevance of cytogenetic markers as prognostic risk factors has been demonstrated in a vast number of studies, with many prognostication tools utilizing these factors to determine treatment approaches....
4.
DA Costa Machado A, Machado C, DE Pinho Pessoa F, Barreto I, Gadelha R, DE Sousa Oliveira D, et al.
Cancer Diagn Progn . 2024 Jan; 4(1):9-24. PMID: 38173664
Leukemias are hematological neoplasms characterized by dysregulations in several cellular signaling pathways, prominently including the PI3K/AKT/mTOR pathway. Since this pathway is associated with several important cellular mechanisms, such as proliferation,...
5.
Machado C, da Silva E, Ferreira W, DE Pinho Pessoa F, de Quadros A, Fantacini D, et al.
Cancers (Basel) . 2023 Dec; 15(23). PMID: 38067214
Detection of t(9;22), and consequent fusion, is still a marker of worse prognosis for acute lymphoblastic leukemia (ALL), with resistance to tyrosine-kinase inhibitor therapy being a major obstacle in the...
6.
DE Pinho Pessoa F, Machado C, Barreto I, Sampaio G, DE Sousa Oliveira D, Ribeiro R, et al.
Biomedicines . 2023 May; 11(4). PMID: 37189716
Acute myeloid leukemia (AML) is a hematologic malignancy that occurs due to alterations such as genetic mutations, chromosomal translocations, or changes in molecular levels. These alterations can accumulate in stem...
7.
Gadelha R, Machado C, DE Pinho Pessoa F, da Costa Pantoja L, Barreto I, Ribeiro R, et al.
Curr Issues Mol Biol . 2022 Nov; 44(11):5498-5515. PMID: 36354684
The WD repeat containing antisense to TP53 () gene codifies an antisense transcript for tumor protein p53 (), stabilization (WRAP53α), and a functional protein (WRAP53β, WDR79, or TCAB1). The WRAP53β...
8.
Barreto I, Machado C, Almeida D, DE Pinho Pessoa F, Gadelha R, da Costa Pantoja L, et al.
Pharmaceutics . 2022 Sep; 14(9). PMID: 36145532
Multiple myeloma (MM) is a blood cell neoplasm characterized by excessive production of malignant monoclonal plasma cells (activated B lymphocytes) by the bone marrow, which end up synthesizing antibodies or...
9.
Sanford A, da Cunha L, Machado C, DE Pinho Pessoa F, Silva A, Ribeiro R, et al.
Int J Mol Sci . 2022 Jul; 23(15). PMID: 35897788
The circadian clock (CC) is a daily system that regulates the oscillations of physiological processes and can respond to the external environment in order to maintain internal homeostasis. For the...
10.
Barreto I, DE Pinho Pessoa F, Machado C, da Costa Pantoja L, Ribeiro R, Lopes G, et al.
Front Oncol . 2022 Jul; 12:931050. PMID: 35814466
Hematopoietic stem cells (HSCs) are known for their ability to proliferate and self-renew, thus being responsible for sustaining the hematopoietic system and residing in the bone marrow (BM). Leukemic stem...