Caiguo Zhang
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Explore the profile of Caiguo Zhang including associated specialties, affiliations and a list of published articles.
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35
Citations
1108
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Recent Articles
1.
Jia X, Wenzlau J, Zhang C, Dong F, Waugh K, Leslie R, et al.
Diabetes
. 2025 Jan;
PMID: 39821270
Increasing evidence shows that pathogenic T cells in type 1 diabetes (T1D) that may have evaded negative selection recognize post-translational modified (PTM) epitopes of self-antigens. We have investigated the profiles...
2.
Jiang R, Li Z, Zhang C, Zhang G, Luo F, Qu Q, et al.
Sci Rep
. 2024 Oct;
14(1):24334.
PMID: 39420067
For a long time, the decline in lung function has been regarded as a potential factor associated with the risk of osteoporosis (OP). Although several observational studies have investigated the...
3.
Jia X, He L, Miao D, Zhang C, Rewers M, Yu L
J Vis Exp
. 2022 Jul;
(185).
PMID: 35876559
An ongoing clinical trial, Autoimmunity Screening for Kids (ASK), is the first screening study in the general population for type 1 diabetes (T1D) and celiac disease in the United States....
4.
Li H, Zhang C, Bian L, Deng H, Blevins M, Han G, et al.
J Invest Dermatol
. 2021 Jul;
142(2):390-401.
PMID: 34293351
Psoriasis is a chronic immune-mediated disease characterized by excessive proliferation of epidermal keratinocytes and increased immune cell infiltration to the skin. Although it is well-known that psoriasis pathogenesis is driven...
5.
Li H, Zhang C, Yang C, Blevins M, Norris D, Zhao R, et al.
Int J Biol Sci
. 2020 Mar;
16(7):1107-1120.
PMID: 32174788
Traumatic brain injury (TBI) induces an acute inflammatory response in the central nervous system that involves both resident and peripheral immune cells. The ensuing chronic neuroinflammation causes cell death and...
6.
Shen L, Xiao Y, Wu Q, Liu L, Zhang C, Pan X
Am J Transl Res
. 2019 Apr;
11(3):1374-1388.
PMID: 30972168
The activation of the toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) signaling pathway has been found to play a critical role in many inflammatory diseases by controlling the expression of...
7.
Liu H, Lu W, He H, Wu J, Zhang C, Gong H, et al.
J Pathol
. 2019 Apr;
248(4):464-475.
PMID: 30945288
Inflammation is well known as an important driver of the initiation of colitis-associated cancer (CAC). Some cytokines, such as IL-6 and TNF-α can activate expression of the oncogene c-Myc (MYC)...
8.
Blevins M, Zhang C, Zhang L, Li H, Li X, Norris D, et al.
Mol Oncol
. 2018 Jun;
12(8):1358-1373.
PMID: 29879296
The carboxyl-terminal binding proteins (CtBP) are transcriptional corepressors that regulate the expression of multiple epithelial-specific and pro-apoptotic genes. Overexpression of CtBP occurs in many human cancers where they promote the...
9.
Chen Z, Zhang W, Jiang K, Chen B, Wang K, Lao L, et al.
Mol Ther Nucleic Acids
. 2018 Mar;
10:254-268.
PMID: 29499938
Cullins, critical members of the cullin-RING ubiquitin ligases (CRLs), are often aberrantly expressed in different cancers. However, the underlying mechanisms regarding aberrant expression of these cullins and the specific substrates...
10.
Zhang C, Chen B, Jiang K, Lao L, Shen H, Chen Z
Mol Oncol
. 2018 Jan;
12(4):476-494.
PMID: 29377600
Cullin 4B, a member of the Cullins, which serve as scaffolds to facilitate the assembly of E3 ligase complexes, is aberrantly expressed in many cancers, including osteosarcoma. Recently, we observed...