C Wofsy
Overview
Explore the profile of C Wofsy including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
37
Citations
391
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hlavacek W, Redondo A, Metzger H, Wofsy C, Goldstein B
Proc Natl Acad Sci U S A
. 2001 Jun;
98(13):7295-300.
PMID: 11390967
In the context of cell signaling, kinetic proofreading was introduced to explain how cells can discriminate among ligands based on a kinetic parameter, the ligand-receptor dissociation rate constant. In the...
2.
Saini S, RICHARDSON J, Wofsy C, Bochner B, MacGlashan Jr D
J Allergy Clin Immunol
. 2001 May;
107(5):832-41.
PMID: 11344350
Background: The IgE receptor (FcepsilonRI) may exist as a tetramer (alphabetagamma2) or a trimer (alphagamma2) because FcepsilonRIbeta is dispensable for membrane expression of FcepsilonRIalpha. FcepsilonRIbeta amplifies signaling of FcepsilonRI so...
3.
Wofsy C, Coombs D, Goldstein B
Biophys J
. 2001 Feb;
80(2):606-12.
PMID: 11159429
The serial engagement model provides an attractive and plausible explanation for how a typical antigen presenting cell, exhibiting a low density of peptides recognized by a T cell, can initiate...
4.
Hlavacek W, Wofsy C, Perelson A
Proc Natl Acad Sci U S A
. 1999 Dec;
96(26):14681-6.
PMID: 10611272
Follicular dendritic cells (FDC) provide a reservoir for HIV type 1 (HIV-1) that may reignite infection if highly active antiretroviral therapy (HAART) is withdrawn before virus on FDC is cleared....
5.
Goldstein B, Coombs D, He X, Pineda A, Wofsy C
J Mol Recognit
. 1999 Nov;
12(5):293-9.
PMID: 10556877
Accurate estimation of biomolecular reaction rates from binding data, when ligands in solution bind to receptors on the surfaces of cells or biosensors, requires an understanding of the contributions of...
6.
Mason T, Pineda A, Wofsy C, Goldstein B
Math Biosci
. 1999 Jul;
159(2):123-44.
PMID: 10414030
Optical biosensors, including the BIACORE, provide an increasingly popular method for determining reaction rates of biomolecules. In a flow chamber, with one reactant immobilized on a chip on the sensor...
7.
One lyn molecule is sufficient to initiate phosphorylation of aggregated high-affinity IgE receptors
Wofsy C, Vonakis B, Metzger H, Goldstein B
Proc Natl Acad Sci U S A
. 1999 Jul;
96(15):8615-20.
PMID: 10411924
In response to antigenic stimuli, the multisubunit immune recognition receptors become aggregated and then phosphorylated on their cytoplasmic tyrosines. For the clonotypic receptors of B and T cells and for...
8.
Metzger H, Chen H, Goldstein B, INMAN J, Peirce M, Torigoe C, et al.
Immunol Lett
. 1999 Jul;
68(1):53-7.
PMID: 10397156
The high affinity receptor for IgE (FcepsilonRI), is one of a family of immunoreceptors whose antigen-induced clustering leads to a variety of cellular responses. The signaling pathways are enormously complex...
9.
Jones G, Wofsy C, Aurell C, Sklar L
Biophys J
. 1999 Jan;
76(1 Pt 1):517-27.
PMID: 9876165
Fluorescence resonance energy transfer (FRET) measurements have been used to analyze fluorophore separations in a number of varying geometries, including small particles and extended surfaces. This study focuses on the...
10.
Wofsy C, Torigoe C, Kent U, Metzger H, Goldstein B
J Immunol
. 1998 Apr;
159(12):5984-92.
PMID: 9550396
When receptors must interact with an extrinsic kinase to initiate signaling, the kinase can play a regulatory role that is not available to intrinsic receptor kinases. Whether control is exercised...