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C Weitzmann

Explore the profile of C Weitzmann including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 52
Followers 0
Related Specialties
Biochemistry
General Medicine
Biology
Top 10 Co-Authors
J OFENGAND
D Negre
K Nurse
P R Cunningham
R Denman
J Colgan
S Ringquist
B S Cooperman
S J Tumminia
L Formenoy
Published In
Biochemistry
Nucleic Acids Res
Proc Natl Acad Sci U S A
Arch Biol Med Exp
J Mol Biol
Affiliations
Soon will be listed here.
Recent Articles
1.
Translation initiation complex formation with 30 S ribosomal particles mutated at conserved positions in the 3'-minor domain of 16 S RNA
Ringquist S, Cunningham P, Weitzmann C, Formenoy L, Pleij C, OFENGAND J, et al.
J Mol Biol . 1993 Nov; 234(1):14-27. PMID: 8230193
Escherichia coli 30 S ribosomal subunits containing in vitro (phage T7 RNA polymerase-generated) 16 S rRNA, both wild-type and mutant, were examined by toeprinting. These synthetic particles were used to...
2.
A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective...
Weitzmann C, Tumminia S, Boublik M, OFENGAND J
Nucleic Acids Res . 1991 Dec; 19(25):7089-95. PMID: 1766869
We have partially purified two 16S rRNA-specific methyltransferases, one of which forms m2G966 (m2G MT), while the other one makes m5C967 (m5C MT). The m2G MT uses unmethylated 30S subunits...
3.
In vitro methylation of Escherichia coli 16S ribosomal RNA and 30S ribosomes
Negre D, Weitzmann C, OFENGAND J
Proc Natl Acad Sci U S A . 1989 Jul; 86(13):4902-6. PMID: 2662188
Treatment of synthetic 30S particles lacking all of the normally methylated nucleotides with S-adenosyl-[3H]methionine and either an S100 or ribosomal high salt wash extract resulted in ribosome-dependent incorporation of [3H]methyl...
4.
Effect of point mutations in the decoding site (C1400) region of 16S ribosomal RNA on the ability of ribosomes to carry out individual steps of protein synthesis
Denman R, Negre D, Cunningham P, Nurse K, Colgan J, Weitzmann C, et al.
Biochemistry . 1989 Feb; 28(3):1012-9. PMID: 2540814
In order to probe the relationship between structure and function of the ribosome, an in vitro system [Denman et al. (1988) Biochemistry (preceding paper in this issue)] was used to...
5.
In vitro assembly of 30S and 70S bacterial ribosomes from 16S RNA containing single base substitutions, insertions, and deletions around the decoding site (C1400)
Denman R, Weitzmann C, Cunningham P, Negre D, Nurse K, Colgan J, et al.
Biochemistry . 1989 Feb; 28(3):1002-11. PMID: 2540813
An in vitro system developed for the site-specific mutagenesis of 16S RNA of Escherichia coli ribosomes [Krzyzosiak et al. (1987) Biochemistry 26, 2353-2364] was used to make 10 single base...
6.
The role of 16S RNA in ribosome function: single base alterations and their effect on in vitro protein synthesis
Cunningham P, Negre D, Weitzmann C, Denman R, Nurse K, OFENGAND J
Arch Biol Med Exp . 1988 Dec; 21(3-4):393-401. PMID: 2476074
An in vitro system developed for the site-specific mutagenesis of 16S RNA of Escherichia coli ribosomes (Krzyzosiak et al., Biochemistry 26, 2353-2364, 1987) was used to make 10 single base...
7.
On the structural specificity of puromycin binding to Escherichia coli ribosomes
Weitzmann C, Cooperman B
Biochemistry . 1985 Apr; 24(9):2268-74. PMID: 3888269
We have examined the structural specificity of the puromycin binding sites on the Escherichia coli ribosome that we have previously identified [Nicholson, A. W., Hall, C. C., Strycharz, W. A.,...