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C W Morgans

Explore the profile of C W Morgans including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 548
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Recent Articles
1.
Guimaraes-Souza E, Perche O, Morgans C, Duvoisin R, Calaza K
Exp Eye Res . 2016 Jan; 146:72-82. PMID: 26719241
Fragile X Mental Retardation Protein (FMRP) is a RNA-binding protein that modulates protein synthesis at the synapse and its function is regulated by glutamate. The retina is the first structure...
2.
Babai N, Morgans C, Thoreson W
Neuroscience . 2009 Nov; 165(4):1447-56. PMID: 19932743
We tested whether calcium-induced calcium release (CICR) contributes to synaptic release from rods in mammalian retina. Electron micrographs and immunofluorescent double labeling for the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA2) and synaptic...
3.
Morgans C
Invest Ophthalmol Vis Sci . 2001 Aug; 42(10):2414-8. PMID: 11527958
Purpose: The molecular identity of the calcium channels that mediate glutamate release from photoreceptors is unknown. Mutations in the recently identified, retina-specific alpha(1F) calcium channel subunit cause incomplete X-linked congenital...
4.
Morgans C, Gaughwin P, Maleszka R
Mol Vis . 2001 Aug; 7:202-9. PMID: 11526344
Purpose: The CACNA1F gene encodes a voltage-gated calcium channel alpha1 subunit, alpha1F, which is expressed in the human retina. Mutations in this gene cause incomplete X-linked congenital stationary night blindness...
5.
Firth S, Morgan I, Boelen M, Morgans C
Clin Exp Ophthalmol . 2001 Jul; 29(3):183-7. PMID: 11446465
L-type calcium channels have been associated with synaptic transmission in the retina, and are a potential site for modulation of the release of neurotransmitters. The present study documents the immunohistochemical...
6.
Morgans C
Immunol Cell Biol . 2000 Aug; 78(4):442-6. PMID: 10947871
The synapses of photoreceptors and bipolar cells in the retina are easily identified ultrastructurally by the presence of synaptic ribbons, electron-dense bars perpendicular to the plasma membrane at the active...
7.
Morgans C
Microsc Res Tech . 2000 Jul; 50(2):141-50. PMID: 10891878
The synapses of photoreceptors and bipolar cells in the retina are characterized ultrastructurally by the presence of an electron-dense bar, the synaptic ribbon, lying perpendicular to the plasma membrane at...
8.
Morgans C
Eur J Neurosci . 1999 Aug; 11(8):2989-93. PMID: 10457194
Retinal photoreceptors are depolarized in darkness and release neurotransmitter tonically. They respond to light by hyperpolarization and a concomitant reduction in transmitter release. The calcium-dependent release of transmitter is coupled...
9.
Morgans C, El Far O, Berntson A, Wassle H, Taylor W
J Neurosci . 1998 Apr; 18(7):2467-74. PMID: 9502807
Ribbon synapses of vertebrate photoreceptors constantly release glutamate in darkness. Transmitter release is maintained by a steady influx of calcium through voltage-dependent calcium channels, implying the presence of a mechanism...
10.
Morgans C, Brandstatter J, Kellerman J, Betz H, Wassle H
J Neurosci . 1996 Nov; 16(21):6713-21. PMID: 8824312
In contrast to conventional synapses, which release neurotransmitter transiently, ribbon synapses formed by photoreceptors and bipolar cells of the retina release neurotransmitter continuously and modulate the rate in response to...