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C Van Geet

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Recent Articles
1.
De Boeck H, Vandendriessche S, Hallin M, Batoko B, Alworonga J, Mapendo B, et al.
Eur J Clin Microbiol Infect Dis . 2015 May; 34(8):1567-72. PMID: 25931131
Methicillin-resistant Staphylococcus aureus (MRSA) is a global health concern, but there are few data from Central Africa. The objective of our study was to characterise S. aureus colonisation isolates from...
2.
Eneman B, Freson K, van den Heuvel L, van Hoyweghen E, Collard L, Vande Walle J, et al.
J Thromb Haemost . 2015 Mar; 13(5):755-67. PMID: 25758343
Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) was recently identified as an inhibitor of megakaryopoiesis and platelet aggregability. Objective: We studied PACAP levels in children with nephrotic syndrome (NS), which is...
3.
Freson K, Wijgaerts A, Van Geet C
Int J Lab Hematol . 2014 Apr; 36(3):313-25. PMID: 24750678
Platelets are derived from megakaryocytes in the bone marrow that create the cellular machinery the platelet needs to participate in the different processes of primary hemostasis including adhesion, activation and...
4.
Phoba M, De Boeck H, Ifeka B, Dawili J, Lunguya O, Vanhoof R, et al.
Eur J Clin Microbiol Infect Dis . 2013 Aug; 33(1):79-87. PMID: 23975545
Salmonella enterica is the leading cause of bloodstream infection in children in sub-Saharan Africa, but few data are available from Central-Africa. We documented during the period November 2011 to May...
5.
Louwette S, Van Geet C, Freson K
J Thromb Haemost . 2012 Aug; 10(11):2215-22. PMID: 22908964
Regulators of G protein signaling (RGS) are intracellular signaling regulators that bind activated G protein α subunits (Gα) and increase their intrinsic GTPase activity via their common RGS homology domain....
6.
Di Michele M, Van Geet C, Freson K
Curr Med Chem . 2012 Jul; 19(27):4662-70. PMID: 22830337
Blood platelets play a fundamental role in primary haemostasis and wound repair, but are also involved in several thrombotic and bleeding disorders for which the underlying mechanisms are still largely...
7.
Izzi B, Van Geet C, Freson K
Curr Mol Med . 2012 Feb; 12(5):566-73. PMID: 22300135
Endocrinopathies in patients with hypocalcemia and hyperphosphatemia that share resistance to parathyroid hormone (PTH) are grouped under the term pseudohypoparathyroidism (PHP). Patients with PHP type Ia (PHP-Ia) often present with...
8.
Noe L, Peeters K, Izzi B, Van Geet C, Freson K
Curr Med Chem . 2010 Sep; 17(26):2897-905. PMID: 20858171
Platelets are indispensable for primary haemostasis, but their function needs to be tightly regulated to prevent excessive platelet activity, possibly leading to atherothrombotic events. An important mediator of the platelet...
9.
Noe L, Di Michele M, Giets E, Thys C, Wittevrongel C, De Vos R, et al.
J Thromb Haemost . 2010 Apr; 8(7):1594-603. PMID: 20403096
Summary Background: Regulator of G-protein signaling (RGS) 2 negatively regulates Gs signaling by inhibiting the activation of adenylyl cyclase (AC). RGS2 mRNA contains four translation initiation sites, leading to four...
10.
Witters P, Hoylaerts M, Freson K, De Vos R, van Pelt J, Nevens F, et al.
J Thromb Haemost . 2009 Nov; 8(2):360-8. PMID: 19895672
Background: The effect of cholestatic liver disease on primary hemostasis function remains ill-defined. Objectives: To determine platelet function and identify the mechanisms involved in the observed platelet function in cholestatic...