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C Unger

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Articles 172
Citations 1970
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Recent Articles
11.
Voegeli R, Echarti C, Maurer H, Stekar J, Hilgard P, Unger C
Int J Oncol . 2011 May; 2(2):161-4. PMID: 21573530
Hexadecylphosphocholine (HPC, D-18506, INN: Miltefosine) was characterized in a clonogenic micro assay in vitro with respect to its cytotoxicity against a panel of human and murine tumor cell lines and...
12.
Gruene M, Pflaum M, Deiwick A, Koch L, Schlie S, Unger C, et al.
Biofabrication . 2011 Mar; 3(1):015005. PMID: 21358040
Laser-assisted bioprinting (LaBP) allows the realization of computer-generated 3D tissue grafts consisting of cells embedded in a hydrogel environment. In this study, human adipose-derived stem cells (hASCs) were printed in...
13.
Elsadek B, Graeser R, Esser N, Schafer-Obodozie C, Tsurumi C, Abu Ajaj K, et al.
Prostate Cancer Prostatic Dis . 2010 Nov; 14(1):14-21. PMID: 21042336
PSA, which is overexpressed in prostate carcinoma, represents a molecular target for selectively releasing an anticancer agent from a prodrug formulation. In this study, we report on the in vivo...
14.
Muller D, Augustin M, Banik N, Baumann W, Bestehorn K, Kieschke J, et al.
Gesundheitswesen . 2010 Sep; 72(11):824-39. PMID: 20872343
On August 30, 2010, the German Network for Health Services Research [Deutsches Netzwerk Versorgungsforschung e. V. (DNVF e. V.)] approved the Memorandum III "Methods for Health Services Research", supported by...
15.
Eldridge D, TITSWORTH E, Unger C
J Bacteriol . 2010 Mar; 53(4):506. PMID: 20342066
No abstract available.
16.
Graeser R, Esser N, Unger H, Fichtner I, Zhu A, Unger C, et al.
Invest New Drugs . 2009 Jan; 28(1):14-9. PMID: 19148580
The (6-maleimidocaproyl)hydrazone derivative of doxorubicin (INNO-206) is an albumin-binding prodrug of doxorubicin with acid-sensitive properties that is being assessed clinically. The prodrug binds rapidly to circulating serum albumin and releases...
17.
Martin-Ibanez R, Unger C, Stromberg A, Baker D, Canals J, Hovatta O
Hum Reprod . 2008 Aug; 23(12):2744-54. PMID: 18716037
Background: Human embryonic stem cells (hESCs) have potential use in clinical therapy and regenerative medicine. One of the major challenges regarding the application of these cells is the development of...
18.
Hedberg M, Svedberg M, Mustafiz T, Yu W, Mousavi M, Guan Z, et al.
Neuroscience . 2008 Jan; 152(1):223-33. PMID: 18164554
Acetylcholinesterase (AChE) is shown to promote deposition of beta-amyloid (Abeta) peptides and to enhance Abeta toxicity. Tg2576 (transgenic mice carrying the Swedish mutation of amyloid precursor protein, APPswe) mice and...
19.
Treschow A, Unger C, Aints A, Felldin U, Aschan J, Dilber M
Gene Ther . 2007 Sep; 14(22):1564-72. PMID: 17898799
Efficient selection of gene-modified cells is required for a number of potential gene therapy applications, as well as molecular biology studies. Ideally, a clinical selection regimen would combine high selection...
20.
Bornmann C, Graeser R, Esser N, Ziroli V, Jantscheff P, Keck T, et al.
Cancer Chemother Pharmacol . 2007 Jun; 61(3):395-405. PMID: 17554540
Despite its rapid enzymatic inactivation and therefore limited activity in vivo, Gemcitabine is the standard drug for pancreatic cancer treatment. To protect the drug, and achieve passive tumor targeting, we...