C Strassel
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Explore the profile of C Strassel including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
158
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Recent Articles
1.
Strassel C, Lanza F, Gachet C
Bull Acad Natl Med
. 2020 Oct;
204(9):971-980.
PMID: 33078027
Blood platelets are anucleated elements of the blood. With a diameter of 2 to 3 μm, they are the smallest elements of blood. While their main role is to stop...
2.
Do Sacramento V, Mallo L, Freund M, Eckly A, Hechler B, Mangin P, et al.
Sci Rep
. 2020 Jan;
10(1):914.
PMID: 31969609
The in vitro production of blood platelets for transfusion purposes is an important goal in the context of a sustained demand for controlled products free of infectious, immune and inflammatory...
3.
Strassel C, Moog S, Mallo L, Eckly A, Freund M, Gachet C, et al.
Sci Rep
. 2018 Oct;
8(1):15808.
PMID: 30361531
Platelets are produced upon profound reorganization of mature megakaryocytes (MK) leading to proplatelet elongation and release into the blood stream, a process termed thrombopoiesis. This highly dynamic process requires microtubules...
4.
Strassel C, Bull A, Moog S, Receveur N, Mallo L, Mangin P, et al.
J Thromb Haemost
. 2016 May;
14(7):1470-9.
PMID: 27148783
Unlabelled: Essentials A signaling role of glycoprotein (GP)Ibβ is postulated but not formally demonstrated in platelets. Lentiviral-mediated rescue in knock-out mice can be used to evaluate GPIbβ function in vivo....
5.
Antkowiak A, Viaud J, Severin S, Zanoun M, Ceccato L, Chicanne G, et al.
J Thromb Haemost
. 2016 Mar;
14(6):1268-84.
PMID: 26991240
Unlabelled: Essentials Information about the formation of the demarcation membrane system (DMS) is still lacking. We investigated the role of the cytoskeleton in DMS structuration in megakaryocytes. Cdc42/Pak-dependent F-actin remodeling...
6.
Pertuy F, Aguilar A, Strassel C, Eckly A, Freund J, Duluc I, et al.
J Thromb Haemost
. 2014 Nov;
13(1):115-25.
PMID: 25393502
Background: Transgenic mice expressing cre recombinase under the control of the platelet factor 4 (Pf4) promoter, in the context of a 100-kb bacterial artificial chromosome, have become a valuable tool...
7.
Strassel C, Hechler B, Bull A, Gachet C, Lanza F
J Thromb Haemost
. 2009 Sep;
7(11):1935-8.
PMID: 19740100
No abstract available.
8.
David T, Strassel C, Eckly A, Cazenave J, Gachet C, Lanza F
J Thromb Haemost
. 2009 Aug;
8(5):1077-87.
PMID: 19694944
Summary Background: Circulating platelets are initially recruited at the site of vessel injury by von Willebrand factor (VWF) immobilized on collagen fibers. This process, mediated by the GPIb-V-IX complex, is...
9.
Strassel C, Nonne C, Eckly A, David T, Leon C, Freund M, et al.
Arterioscler Thromb Vasc Biol
. 2006 Nov;
27(1):241-7.
PMID: 17095718
Objective: The platelet glycoprotein (GP)Ib-V-IX complex is a receptor required for normal hemostasis deficient in the Bernard-Soulier bleeding disorder. To evaluate the consequences of GPIb-V-IX deficiency in thrombosis we generated...
10.
Strassel C, David T, Eckly A, Baas M, Moog S, Ravanat C, et al.
J Thromb Haemost
. 2006 Jan;
4(1):217-28.
PMID: 16409472
The molecular defect of a new Bernard-Soulier patient, originating from Morocco and presenting thrombocytopenia with large platelets and an absence of ristocetin-induced platelet agglutination, has been identified and reproduced in...