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C Stirzaker

Explore the profile of C Stirzaker including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 307
Followers 0
Related Specialties
Oncology
Biochemistry
Molecular Biology
Top 10 Co-Authors
S J Clark
J Harrison
J Z Song
N J Armstrong
D S Millar
C L Paul
P M Warnecke
F Valdes-Mora
R L Sutherland
T Sibbritt
Published In
Oncogene
Cancer Res
Nucleic Acids Res
Anal Biochem
Affiliations
Soon will be listed here.
Recent Articles
1.
Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer
Stirzaker C, Song J, Ng W, Du Q, Armstrong N, Locke W, et al.
Oncogene . 2016 Sep; 36(10):1328-1338. PMID: 27593931
Cancer is characterised by DNA hypermethylation and gene silencing of CpG island-associated promoters, including tumour-suppressor genes. The methyl-CpG-binding domain (MBD) family of proteins bind to methylated DNA and can aid...
2.
Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer
Hulf T, Sibbritt T, Wiklund E, Patterson K, Song J, Stirzaker C, et al.
Oncogene . 2012 Aug; 32(23):2891-9. PMID: 22869146
Deregulation of microRNA (miRNA) expression can have a critical role in carcinogenesis. Here we show in prostate cancer that miRNA-205 (miR-205) transcription is commonly repressed and the MIR-205 locus is...
3.
Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts
Harrison J, Stirzaker C, Clark S
Anal Biochem . 1998 Oct; 264(1):129-32. PMID: 9784198
No abstract available.
4.
Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA
Warnecke P, Stirzaker C, Melki J, Millar D, Paul C, Clark S
Nucleic Acids Res . 1997 Oct; 25(21):4422-6. PMID: 9336479
Methylation analysis of individual cytosines in genomic DNA can be determined quantitatively by bisulphite treatment and PCR amplification of the target DNA sequence, followed by restriction enzyme digestion or sequencing....
5.
Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors
Stirzaker C, Millar D, Paul C, Warnecke P, Harrison J, Vincent P, et al.
Cancer Res . 1997 Jun; 57(11):2229-37. PMID: 9187126
The retinoblastoma gene (Rb) is one of the best characterized tumor suppressor genes, and its inactivation is associated with a number of cancers. Previous studies have shown, by restriction enzyme...