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C R Roland

Explore the profile of C R Roland including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 85
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Recent Articles
1.
Roland C, Nakafusa Y, Flye M
J Gastrointest Surg . 1999 Sep; 3(3):301-7. PMID: 10481123
The monocytic phagocytic system, consisting primarily of tissue macrophages of the liver and spleen, produces prostaglandin E(2) (PGE(2)), a modulator of the septic response. Macrophages are known to internalize gadolinium...
2.
Roland C, Naziruddin B, Mohanakumar T, Flye M
Hepatology . 1999 Mar; 29(3):756-65. PMID: 10051477
Hepatic Kupffer cells (KC), the major tissue macrophage population, produce the septic response mediators, tumor necrosis factor alpha (TNF-alpha) and prostaglandin E2 (PGE2), and have been shown to internalize gadolinium...
3.
Roland C, Naziruddin B, Mohanakumar T, Flye M
J Leukoc Biol . 1996 Oct; 60(4):487-92. PMID: 8864133
Kupffer cells (KC) are the phagocytic macrophages of the liver. The rare earth metal, gadolinium (GdCl3), is a lanthanide, which, after phagocytosis by the KC, has been found to alter...
4.
Roland C, Walp L, Stack R, Flye M
J Immunol . 1994 Dec; 153(12):5453-64. PMID: 7527442
The interaction between lymphocytes and the resident hepatic macrophage, the Kupffer cell (KC), is relevant to the phenomenon of immune tolerance to Ags entering the liver. Tolerance to Ag administered...
5.
Goss J, Nakafusa Y, Roland C, Hickey W, Flye M
J Immunol . 1994 Nov; 153(9):3890-8. PMID: 7523508
To explore the mechanisms responsible for the development of tolerance to allografts after intrathymic (IT) injection of alloantigen, the well-defined model of experimental autoimmune encephalomyelitis (EAE), which mimics the human...
6.
Hafenrichter D, Roland C, Mangino M, Flye M
Shock . 1994 Oct; 2(4):251-6. PMID: 7757516
Kupffer cells (KC) of the hepatic sinusoid respond to endotoxemia by producing mediators which promote or inhibit systemic inflammatory responses. Sublethal lipopolysaccharide (LPS) pretreatment confers tolerance to the lethality of...
7.
Nakafusa Y, Goss J, Roland C, Flye M
Transplant Proc . 1994 Jun; 26(3):1621. PMID: 8030061
No abstract available.
8.
Roland C, Goss J, Mangino M, Hafenrichter D, Flye M
Ann Surg . 1994 Apr; 219(4):389-99. PMID: 8161265
Objective: Methods employed previously to analyze the secretory behavior of rodent Kupffer cells (KC) were used to examine the human KC's secretory response to lipopolysaccharide (LPS). Summary Background Data: As...
9.
Nakafusa Y, Goss J, Roland C, Flye M
Transplantation . 1993 Nov; 56(5):1279-82. PMID: 8249139
No abstract available.
10.
Roland C, Mangino M, Duffy B, Flye M
Transplantation . 1993 May; 55(5):1151-8. PMID: 8388586
Ag administration into the portal vein can induce specific tolerance to that Ag, known as portal venous tolerance. Because intrahepatic mechanisms of tolerance induction are still largely undefined, we studied...