C R Dunstan
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Explore the profile of C R Dunstan including associated specialties, affiliations and a list of published articles.
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83
Citations
8133
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Recent Articles
1.
Scheiner S, Pivonka P, Smith D, Dunstan C, Hellmich C
Int J Numer Method Biomed Eng
. 2013 Sep;
30(1):1-27.
PMID: 24039120
Denosumab, a fully human monoclonal antibody, has been approved for the treatment of postmenopausal osteoporosis. The therapeutic effect of denosumab rests on its ability to inhibit osteoclast differentiation. Here, we...
2.
Roohani-Esfahani S, Dunstan C, Li J, Lu Z, Davies B, Pearce S, et al.
Acta Biomater
. 2013 Mar;
9(6):7014-24.
PMID: 23467040
During the past two decades, research on ceramic scaffolds for bone regeneration has progressed rapidly; however, currently available porous scaffolds remain unsuitable for load-bearing applications. The key to success is...
3.
Roohani-Esfahani S, Dunstan C, Davies B, Pearce S, Williams R, Zreiqat H
Acta Biomater
. 2012 Jul;
8(11):4162-72.
PMID: 22842031
This is the first reported study to prepare highly porous baghdadite (Ca₃ZrSi₂O₉) scaffolds with and without surface modification and investigate their ability to repair critical-sized bone defects in a rabbit...
4.
Blair J, Zheng Y, Dunstan C
Int J Biochem Cell Biol
. 2006 Dec;
39(6):1077-81.
PMID: 17174136
RANK ligand (RANKL), a key mediator of bone resorption in normal and pathological states, is expressed as membrane-bound or soluble forms by tissues as diverse as lymph nodes, spleen, thymus...
5.
Dunstan C, Walpole R
Int J Obstet Anesth
. 2006 Nov;
16(1):93-4.
PMID: 17126546
No abstract available.
6.
Geusens P, Landewe R, Garnero P, Chen D, Dunstan C, Lems W, et al.
Arthritis Rheum
. 2006 Jun;
54(6):1772-7.
PMID: 16736519
Objective: Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in debilitating joint deformities with destruction of bone and cartilage. Inflammation is still considered the pivotal inducer of...
7.
Valenta A, Roschger P, Fratzl-Zelman N, Kostenuik P, Dunstan C, Fratzl P, et al.
Bone
. 2005 May;
37(1):87-95.
PMID: 15869920
The combination of PTH with OPG has been proposed as a potential therapy in patients with severe osteoporosis. In the present study, we examined the bone material of aged ovariectomized...
8.
Kiefer J, Vessella R, Quinn J, Odman A, Zhang J, Keller E, et al.
Clin Exp Metastasis
. 2005 Jan;
21(5):381-7.
PMID: 15672862
Osteoprotegerin (OPG) plays a central role in controlling bone resorption. Exogenous administration of OPG has been shown to be effective in preventing osteolysis and limiting the growth of osteolytic metastasis....
9.
Ross A, Bateman T, Kostenuik P, Ferguson V, Lacey D, Dunstan C, et al.
J Mater Sci Mater Med
. 2004 Sep;
12(7):583-8.
PMID: 15348250
Osteoprotegerin (OPG) is a naturally secreted protein that decreases bone resorption by inhibiting osteoclast differentiation and activation while promoting osteoclast apoptosis [8]. In this study, the effects of osteoprotegerin injections...
10.