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C R Bruce

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Articles 22
Citations 1107
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Recent Articles
11.
Matthews V, Astrom M, Chan M, Bruce C, Krabbe K, Prelovsek O, et al.
Diabetologia . 2009 Apr; 52(7):1409-18. PMID: 19387610
Aims/hypothesis: Brain-derived neurotrophic factor (BDNF) is produced in skeletal muscle, but its functional significance is unknown. We aimed to determine the signalling processes and metabolic actions of BDNF. Methods: We...
12.
Carey A, Petersen E, Bruce C, Southgate R, Pilegaard H, Hawley J, et al.
Diabetologia . 2006 Mar; 49(5):1000-7. PMID: 16538490
Aims/hypothesis: We compared metabolic gene expression in adipose tissue and skeletal muscle from patients with type 2 diabetes and from well-matched healthy control subjects. We hypothesised that gene expression would...
13.
Dyck D, Heigenhauser G, Bruce C
Acta Physiol (Oxf) . 2006 Feb; 186(1):5-16. PMID: 16497175
Several adipose-derived cytokines (adipokines) have been suggested to act as a link between accumulated fat mass and altered insulin sensitivity. Resistin and tumour necrosis factor-alpha (TNF-alpha) have been implicated in...
14.
Carey A, Bruce C, Sacchetti M, Anderson M, Olsen D, Saltin B, et al.
Diabetologia . 2004 May; 47(6):1029-37. PMID: 15168015
Aims/hypothesis: Our aim was to examine the possible direct relationship of interleukin-6 and TNFalpha with insulin sensitivity in humans. Methods: We carried out two series of euglycaemic-hyperinsulinaemic clamp experiments. In...
15.
Wadley G, Bruce C, Konstantopoulos N, Macaulay S, Howlett K, Hawley J, et al.
Diabetologia . 2004 Jan; 47(3):412-419. PMID: 14730380
Aims/hypothesis: Recruitment of the protein c-Cbl to the insulin receptor (IR) and its tyrosine phosphorylation via a pathway that is independent from phosphatidylinositol 3'-kinase is necessary for insulin-stimulated GLUT4 translocation...
16.
Bruce C, Kriketos A, Cooney G, Hawley J
Diabetologia . 2003 Dec; 47(1):23-30. PMID: 14673522
Aim/hypothesis: We determined the effect of exercise training on insulin sensitivity and muscle lipids (triglyceride [TG(m)] and long-chain fatty acyl CoA [LCACoA] concentration) in patients with Type 2 diabetes. Methods:...
17.
Lee J, Bruce C, Tunstall R, Cameron-Smith D, Hugel H, Hawley J
Acta Physiol Scand . 2002 May; 175(1):37-44. PMID: 11982503
We determined the interaction of exercise and diet on glucose transporter (GLUT-4) protein and mRNA expression in type I (soleus) and type II [extensor digitorum longus (EDL)] skeletal muscle. Forty-eight...
18.
Arkinstall M, Bruce C, Nikolopoulos V, Garnham A, Hawley J
J Appl Physiol (1985) . 2001 Oct; 91(5):2125-34. PMID: 11641353
The effects of carbohydrate or water ingestion on metabolism were investigated in seven male subjects during two running and two cycling trials lasting 60 min at individual lactate threshold using...
19.
Bruce C, Lee J, Hawley J
J Appl Physiol (1985) . 2001 Sep; 91(4):1512-9. PMID: 11568131
We determined the effect of an acute bout of swimming (8 x 30 min) followed by either carbohydrate administration (0.5 mg/g glucose ip and ad libitum access to chow; CHO)...
20.
Lee J, Bruce C, Spriet L, Hawley J
Exp Physiol . 2001 Jul; 86(4):499-508. PMID: 11445829
We determined the interaction of diet and training on metabolic adaptations in skeletal muscle and liver, and the consequences of these adaptations for endurance. Eighty rats performed a baseline treadmill...