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C Q Edwards

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Articles 62
Citations 984
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Recent Articles
1.
Weires M, Tausch B, Haug P, Edwards C, Wetter T, Cannon-Albright L
Exp Clin Endocrinol Diabetes . 2007 Dec; 115(10):634-40. PMID: 18058597
The aims of this study were to estimate relative risk for type 1 and type 2 diabetes in relatives of diabetic patients, and to test for excess relatedness among diabetic...
2.
Bulaj Z, Franklin M, Phillips J, Miller K, Bergonia H, Ajioka R, et al.
J Lab Clin Med . 2000 Dec; 136(6):482-8. PMID: 11128750
Oral contraceptives and postmenopausal estrogen replacement therapy are recognized as risk factors for the development of porphyria cutanea tarda (PCT) in women. The recommended clinical practice is to withhold estrogen...
3.
Bulaj Z, Ajioka R, Phillips J, LaSalle B, Jorde L, Griffen L, et al.
N Engl J Med . 2000 Nov; 343(21):1529-35. PMID: 11087882
Background: Hemochromatosis occurs in approximately 5 white people per 1000 and is usually due to homozygosity for mutations in the HLA-linked HFE gene. Although screening has been proposed, the proportion...
4.
Bulaj Z, Phillips J, Ajioka R, Franklin M, Griffen L, Guinee D, et al.
Blood . 2000 Feb; 95(5):1565-71. PMID: 10688809
Inherited and acquired factors have been implicated in the pathogenesis of porphyria cutanea tarda (PCT), a disorder characterized by a photosensitive dermatosis and hepatic siderosis. This study, comprising 108 patients...
5.
McDonnell S, Grindon A, Preston B, Barton J, Edwards C, Adams P
Transfusion . 1999 Jun; 39(6):651-6. PMID: 10378847
Background: One in 10 whites in the United States is a carrier for hemochromatosis and an estimated 1 in 200 is clinically affected. Early treatment with therapeutic phlebotomy to remove...
6.
McDonnell S, Preston B, Jewell S, Barton J, Edwards C, Adams P, et al.
Am J Med . 1999 Jun; 106(6):619-24. PMID: 10378618
Purpose: Hemochromatosis is a genetic disorder of iron absorption that affects 5 per 1,000 persons and is associated with reduced health and quality of life. We sought to determine the...
7.
Barton J, McDonnell S, Adams P, Brissot P, Powell L, Edwards C, et al.
Ann Intern Med . 1998 Dec; 129(11):932-9. PMID: 9867745
The complications of iron overload in hemochromatosis can be avoided by early diagnosis and appropriate management. Therapeutic phlebotomy is used to remove excess iron and maintain low normal body iron...
8.
Edwards C, Griffen L, Ajioka R, Kushner J
Semin Hematol . 1998 Feb; 35(1):72-6. PMID: 9460810
Hereditary hemochromatosis is one of the most common inherited disorders among Caucasians of European ancestry. Malregulation of iron absorption from the duodenum eventually leads to iron overload. Although the time...
9.
Ajioka R, Jorde L, Gruen J, Yu P, Dimitrova D, Barrow J, et al.
Am J Hum Genet . 1997 Jun; 60(6):1439-47. PMID: 9199565
We applied several types of linkage-disequilibrium calculations to analyze the hereditary hemochromatosis (hh) locus. Twenty-four polymorphic markers in the major histocompatibility complex (MHC) class I region were used to haplotype...
10.
Ajioka R, Yu P, Gruen J, Edwards C, Griffen L, Kushner J
J Med Genet . 1997 Jan; 34(1):28-33. PMID: 9032646
Hereditary haemochromatosis (HFE) is a common inherited disorder, affecting approximately five per thousand white people of northern European descent. Genetic linkage and linkage disequilibrium studies indicate that the disease locus...