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C Perreault

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Articles 98
Citations 552
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Recent Articles
1.
Granados D, Rodenbrock A, Laverdure J, Cote C, Caron-Lizotte O, Carli C, et al.
Leukemia . 2016 Feb; 30(6):1344-54. PMID: 26857467
Pre-clinical studies have shown that injection of allogeneic T cells primed against a single minor histocompatibility antigen (MiHA) could cure hematologic cancers (HC) without causing any toxicity to the host....
2.
Pilon E, Dieude M, Qi S, Hamelin K, Pomerleau L, Beillevaire D, et al.
Am J Transplant . 2015 Mar; 15(5):1205-18. PMID: 25808553
Transplant vasculopathy is associated with neointimal accumulation of recipient-derived mesenchymal stem cells. Increased circulating levels of LG3, a C-terminal fragment of perlecan, were found in renal transplant patients with vascular...
3.
Delisle J, Giroux M, Boucher G, Landry J, Hardy M, Lemieux S, et al.
Genes Immun . 2013 Jan; 14(2):115-26. PMID: 23328844
Transforming growth factor-β (TGF-β) maintains self-tolerance through a constitutive inhibitory effect on T-cell reactivity. In most physiological situations, the tolerogenic effects of TGF-β depend on the canonical signaling molecule Smad3....
4.
Busque L, Belisle C, Provost S, Giroux M, Perreault C
Genes Immun . 2009 Jan; 10(2):192-6. PMID: 19129849
As a key component of the transforming growth factor-beta (TGF-beta) pathway, SMAD3 plays an essential role in development and maintenance of self-tolerance. Furthermore, a recent study based on gene-expression profiling...
5.
Le Blanc R, Belanger R, Busque L, Fish D, Roy D, Kassis J, et al.
Bone Marrow Transplant . 2002 Jan; 28(9):841-8. PMID: 11781644
We report a series of 37 consecutive patients with multiple myeloma (MM) who received an allograft between 1990 and 2000 at our institution. Median age was 47 years, and nearly...
6.
Meunier M, Lanteigne A, Brochu S, Perreault C
Eur J Immunol . 2001 Jul; 31(8):2284-92. PMID: 11477540
The presence of dominant epitopes suppresses generation of CTL activity toward other non-dominant epitopes found on the same antigen-presenting cell (APC). This phenomenon, termed immunodomination, drastically restricts the diversity of...
7.
Fontaine P, Knafo L, Baron C, Roy D, Perreault C
Nat Med . 2001 Jul; 7(7):789-94. PMID: 11433342
Adoptive transfer of T cells reactive to minor histocompatibility antigens has the unmatched ability to eradicate malignant hematopoietic cells. Unfortunately, its use is hampered by the associated graft-versus-host disease. The...
8.
Gyger M, Stuart R, Perreault C
Bone Marrow Transplant . 2000 Aug; 26(1):1-16. PMID: 10918400
The use of mobilized peripheral blood (PB) stem cells for autologous transplantation initially generated much enthusiasm because of enhanced engraftment in comparison to marrow stem cells and avoidance of general...
9.
Guimond M, Busque L, Baron C, Bonny Y, Belanger R, Mattioli J, et al.
Br J Haematol . 2000 Jun; 109(1):130-7. PMID: 10848792
Donor lymphocyte infusions are particularly effective for remission induction in malignant cells in patients who relapse after allogeneic progenitor cell transplantation (PCT) and who remain sensitive to the administration of...
10.
Boileau C, Houde M, Dulude G, Clegg C, Perreault C
J Immunol . 2000 May; 164(11):5713-20. PMID: 10820248
Chronic exposure to oncostatin M (OM) has been shown to stimulate extrathymic T cell development. The present work shows that in OM transgenic mice, 1) massive extrathymic T cell development...