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C N Tomes

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Articles 8
Citations 129
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Recent Articles
1.
Belmonte S, Lopez C, Roggero C, De Blas G, Tomes C, Mayorga L
Dev Biol . 2005 Aug; 285(2):393-408. PMID: 16099449
The acrosome is an exocytic granule that overlies the spermatozoan nucleus. In response to different stimuli, it undergoes calcium-regulated exocytosis. Freshly ejaculated mammalian sperm are not immediately capable of undergoing...
2.
Tomes C, De Blas G, Michaut M, Farre E, Cherhitin O, Visconti P, et al.
Mol Hum Reprod . 2004 Nov; 11(1):43-51. PMID: 15542541
The acrosome is a membrane-limited granule that overlies the nucleus of the mature spermatozoon. In response to physiological or pharmacological stimuli it undergoes a special type of Ca2+-dependent exocytosis termed...
3.
Tomes C, Roggero C, de Blas G, Saling P, Mayorga L
Dev Biol . 2004 Jan; 265(2):399-415. PMID: 14732401
The acrosome is a membrane-limited granule that overlies the nucleus of the mature spermatozoon. In response to physiological or pharmacological stimuli, sperm undergo calcium-dependent exocytosis termed the acrosome reaction, which...
4.
Michaut M, de Blas G, Tomes C, Yunes R, Fukuda M, Mayorga L
Dev Biol . 2001 Jul; 235(2):521-9. PMID: 11437455
Acrosomal exocytosis is a calcium-dependent secretion event causing the release of the acrosomal contents and the loss of the membranes surrounding the acrosome. The synaptotagmins are a family of calcium-binding...
5.
Michaut M, Tomes C, de Blas G, Yunes R, Mayorga L
Proc Natl Acad Sci U S A . 2000 Aug; 97(18):9996-10001. PMID: 10954749
The acrosome reaction of spermatozoa is a complex, calcium-dependent, regulated exocytosis. Fusion at multiple sites between the outer acrosomal membrane and the cell membrane causes the release of the acrosomal...
6.
Tomes C, Carballada R, Moses D, Katz D, Saling P
Mol Hum Reprod . 1998 Mar; 4(1):17-25. PMID: 9510007
It has long been known that seminal plasma contains factors that influence the fertilizing capacity of spermatozoa in many different ways. However, little is understood of the biochemical cascades triggered...
7.
Tomes C, McMaster C, Saling P
Mol Reprod Dev . 1996 Feb; 43(2):196-204. PMID: 8824918
Many cellular responses to the occupancy of membrane receptors include the hydrolysis of phosphatidylinositol-4,5 bisphosphate (PIP2) by phospholipase C (PLC) and the subsequent generation of inositol 1,4,5-triphosphate (IP3) and diacylglycerol...
8.
Pomilio A, Buschi C, Tomes C, Viale A
J Ethnopharmacol . 1992 Apr; 36(2):155-61. PMID: 1608273
The antimicrobial activity of extracts and constituents of Gomphrena martiana and Gomphrena boliviana (Amaranthaceae) were determined in order to identify the compounds responsible for the folk-medicinal use of these plants....