C N Leitao
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Explore the profile of C N Leitao including associated specialties, affiliations and a list of published articles.
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25
Citations
310
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0
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Recent Articles
1.
Chaves P, Cruz C, Dias Pereira A, Suspiro A, de Almeida J, Leitao C, et al.
Dis Esophagus
. 2005 Dec;
18(6):383-7.
PMID: 16336609
Intestinal metaplasia is a prerequisite criterion for the diagnosis of Barrett's metaplasia and the sole columnar esophageal lining associated with malignancy. It is recognized by the presence of goblet cells,...
2.
Chaves P, Cruz C, Cardoso P, Suspiro A, Dias Pereira A, Mendes de Almeida J, et al.
J Exp Clin Cancer Res
. 2003 Jul;
22(2):273-8.
PMID: 12866578
Barrett's epithelium (BE), the esophageal columnar-lining with intestinal differentiation, is a premalignant condition predisposing to adenocarcinoma. Columnar cells are the prevalent element of BE, but the hallmark of intestinal differentiation...
3.
Chaves P, Dias Pereira A, Cruz C, Suspiro A, Mendes de Almeida J, Leitao C, et al.
Dis Esophagus
. 2002 Dec;
15(4):282-6.
PMID: 12472472
Barrett's metaplasia is recognized by specialized columnar epithelium on the distal esophagus. The events involved in the transformation from squamous to Barrett's epithelium remain unclear. The present study describes the...
4.
Chaves P, Cruz C, Lage P, Claro I, Cravo M, Leitao C, et al.
J Pathol
. 2000 Aug;
191(4):355-60.
PMID: 10918209
There are two well-defined pathways for colorectal carcinogenesis, the suppressor and the mutator pathways. The latter is characteristic of hereditary non-polyposis colorectal cancer (HNPCC), but can also be found in...
5.
Fidalgo P, Almeida M, West S, Gaspar C, Maia L, Wijnen J, et al.
Eur J Hum Genet
. 2000 Mar;
8(1):49-53.
PMID: 10713887
Mutation searching was performed in the hMSH2 and hMLH1 genes in 20 Portuguese families representing 124 registered affected individuals. Of the 20, 16 fulfilled the classic 'Amsterdam' criteria for HNPCC,...
6.
Chaves P, Cardoso P, Almeida J, Pereira A, Leitao C, Soares J
Hum Pathol
. 1999 Nov;
30(11):1291-5.
PMID: 10571507
Barrett's esophagus develops with the following 2 distinct types of lining mucosa: with and without specialized intestinal metaplasia (SIM). Goblet cells found only in SIM areas identify an intestinal phenotype,...
7.
Pinto A, Fidalgo P, Cravo M, Midoes J, Chaves P, Rosa J, et al.
Dis Colon Rectum
. 1999 Jun;
42(6):788-95; discussion 795-6.
PMID: 10378604
Purpose: Short chain fatty acids are the main energy source of colonocytes and their use may be impaired in chronic radiation proctitis. The aim of the present study was to...
8.
Suspiro A, Fidalgo P, Cravo M, Albuquerque C, Ramalho E, Leitao C, et al.
Am J Gastroenterol
. 1998 Sep;
93(9):1572-4.
PMID: 9732950
The Muir-Torre syndrome is a rare autosomal dominant disorder characterized by the association of visceral malignancies with typical skin lesions. This syndrome is now considered a subtype of the more...
9.
Pereira A, Suspiro A, Chaves P, Saraiva A, Gloria L, Almeida J, et al.
Gut
. 1998 Jul;
42(5):659-62.
PMID: 9659160
Background: Endoscopic diagnosis of short segments of Barrett's epithelium (SSBE)' is difficult and its meaning in terms of the presence of specialised columnar epithelium (SCE) has not been prospectively evaluated....
10.
Cristovao L, Lechner M, Fidalgo P, Leitao C, Mira F, Rueff J
Br J Cancer
. 1998 Jul;
77(10):1628-32.
PMID: 9635838
Poly(ADP-ribose)polymerase (PARP) has been implicated in DNA repair mechanisms and the associated activity shown to markedly increase after DNA damage in carcinogen-treated cells. A defective DNA repair has been associated...