C Michael Stein
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Explore the profile of C Michael Stein including associated specialties, affiliations and a list of published articles.
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249
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7128
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Recent Articles
11.
Yan C, Grabowska M, Dickson A, Li B, Wen Z, Roden D, et al.
NPJ Digit Med
. 2024 Feb;
7(1):46.
PMID: 38409350
Drug repurposing represents an attractive alternative to the costly and time-consuming process of new drug development, particularly for serious, widespread conditions with limited effective treatments, such as Alzheimer's disease (AD)....
12.
Yan C, Ong H, Grabowska M, Krantz M, Su W, Dickson A, et al.
medRxiv
. 2024 Jan;
PMID: 38196578
Objectives: Phenotyping is a core task in observational health research utilizing electronic health records (EHRs). Developing an accurate algorithm demands substantial input from domain experts, involving extensive literature review and...
13.
Ray W, Fuchs D, Olfson M, Patrick S, Stein C, Murray K, et al.
JAMA Psychiatry
. 2023 Nov;
81(3):260-269.
PMID: 38019523
Importance: Dose-related effects of antipsychotic medications may increase mortality in children and young adults. Objective: To compare mortality for patients aged 5 to 24 years beginning treatment with antipsychotic vs...
14.
Bathon J, Centola M, Liu X, Jin Z, Ji W, Knowlton N, et al.
Arthritis Res Ther
. 2023 Oct;
25(1):213.
PMID: 37899440
Background: Cardiovascular (CV) risk estimation calculators for the general population underperform in patients with rheumatoid arthritis (RA). The purpose of this study was to identify relevant protein biomarkers that could...
15.
Jiang L, Liu G, Oeser A, Ihegword A, Dickson A, Daniel L, et al.
Elife
. 2023 Oct;
12.
PMID: 37882666
Background: Two risk variants in the apolipoprotein L1 gene () have been associated with increased susceptibility to sepsis in Black patients. However, it remains unclear whether high-risk genotypes are associated...
16.
Mosley J, Shelley J, Dickson A, Zanussi J, Daniel L, Zheng N, et al.
medRxiv
. 2023 Sep;
PMID: 37662324
Polygenic variation unrelated to disease contributes to interindividual variation in baseline white blood cell (WBC) counts, but its clinical significance is undefined. We investigated the clinical consequences of a genetic...
17.
Zanussi J, Zhao J, Wei W, Karakoc G, Chung C, Feng Q, et al.
BMC Rheumatol
. 2023 Aug;
7(1):24.
PMID: 37550754
Background: Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals...
18.
Corriere M, Daniel L, Dickson A, Nepal P, Hall K, Plummer W, et al.
Clin Pharmacol Ther
. 2023 Aug;
114(5):1050-1057.
PMID: 37548889
Gabapentin is prescribed for pain and is perceived as safe generally. However, gabapentin can cause respiratory depression, exacerbated by concomitant central nervous system depressants (e.g., opioids), a concern for vulnerable...
19.
Yan C, Grabowska M, Dickson A, Li B, Wen Z, Roden D, et al.
medRxiv
. 2023 Jul;
PMID: 37461512
Drug repurposing represents an attractive alternative to the costly and time-consuming process of new drug development, particularly for serious, widespread conditions with limited effective treatments, such as Alzheimer's disease (AD)....
20.
Ray W, Chung C, Stein C, Smalley W, Zimmerman E, Dupont W, et al.
Ann Intern Med
. 2023 May;
176(6):769-778.
PMID: 37216662
Background: Amiodarone, the most effective antiarrhythmic drug in atrial fibrillation, inhibits apixaban and rivaroxaban elimination, thus possibly increasing anticoagulant-related risk for bleeding. Objective: For patients receiving apixaban or rivaroxaban, to...