C Mark Ott
Overview
Explore the profile of C Mark Ott including associated specialties, affiliations and a list of published articles.
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42
Citations
1770
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Recent Articles
1.
Nickerson C, McLean R, Barrila J, Yang J, Thornhill S, Banken L, et al.
Microbiol Mol Biol Rev
. 2024 Aug;
88(3):e0014423.
PMID: 39158275
SUMMARYUnderstanding the dynamic adaptive plasticity of microorganisms has been advanced by studying their responses to extreme environments. Spaceflight research platforms provide a unique opportunity to study microbial characteristics in new...
2.
Yang J, Barrila J, Nauman E, Nydam S, Yang S, Park J, et al.
Gut Microbes
. 2024 May;
16(1):2357767.
PMID: 38783686
The ability of bacteria to sense and respond to mechanical forces has important implications for pathogens during infection, as they experience wide fluid shear fluctuations in the host. However, little...
3.
Franco Melendez K, Crenshaw K, Barrila J, Yang J, Gangaraju S, Davis R, et al.
mSphere
. 2022 Aug;
7(4):e0021022.
PMID: 35913142
The discovery that biomechanical forces regulate microbial virulence was established with the finding that physiological low fluid shear (LFS) forces altered gene expression, stress responses, and virulence of the enteric...
4.
Barrila J, Yang J, Franco Melendez K, Yang S, Buss K, Davis T, et al.
Front Cell Infect Microbiol
. 2022 Jun;
12:705647.
PMID: 35711662
Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection. However, our mechanistic understanding...
5.
Nickerson C, Medina-Colorado A, Barrila J, Poste G, Ott C
Nat Microbiol
. 2021 Dec;
7(4):471-474.
PMID: 34903836
No abstract available.
6.
Yang J, Barrila J, Ott C, King O, Bruce R, McLean R, et al.
NPJ Biofilms Microbiomes
. 2021 Sep;
7(1):70.
PMID: 34489467
While sequencing technologies have revolutionized our knowledge of microbial diversity, little is known about the dynamic emergent phenotypes that arise within the context of mixed-species populations, which are not fully...
7.
Barrila J, Sarker S, Hansmeier N, Yang S, Buss K, Briones N, et al.
NPJ Microgravity
. 2021 Mar;
7(1):9.
PMID: 33750813
Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to infectious disease. However, the influence of this environment on host-pathogen...
8.
Makedonas G, Mehta S, Chouker A, Simpson R, Marshall G, Orange J, et al.
Front Immunol
. 2019 Nov;
10:2407.
PMID: 31681296
No abstract available.
9.
Voorhies A, Ott C, Mehta S, Pierson D, Crucian B, Feiveson A, et al.
Sci Rep
. 2019 Jul;
9(1):9911.
PMID: 31289321
Over the course of a mission to the International Space Station (ISS) crew members are exposed to a number of stressors that can potentially alter the composition of their microbiomes...
10.
Tirumalai M, Karouia F, Tran Q, Stepanov V, Bruce R, Ott C, et al.
mBio
. 2019 Jan;
10(1).
PMID: 30647159
The long-term response of microbial communities to the microgravity environment of space is not yet fully understood. Of special interest is the possibility that members of these communities may acquire...