C Mackie
Overview
Explore the profile of C Mackie including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
173
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Recent Articles
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2.
Gregory K, Herman E, Ramsey A, Hammond A, Byun N, Stauffer S, et al.
J Pharmacol Exp Ther
. 2013 Aug;
347(2):438-57.
PMID: 23965381
Impaired transmission through glutamatergic circuits has been postulated to play a role in the underlying pathophysiology of schizophrenia. Furthermore, inhibition of the N-methyl-d-aspartate (NMDA) subtype of ionotropic glutamate receptors (NMDAR)...
3.
Sekar S, Jonckers E, Verhoye M, Willems R, Veraart J, Van Audekerke J, et al.
Psychopharmacology (Berl)
. 2013 Jan;
227(3):479-91.
PMID: 23354531
Background: An effective NMDA antagonist imaging model may find key utility in advancing schizophrenia drug discovery research. We investigated effects of subchronic treatment with the NMDA antagonist memantine by using...
4.
Rhind S, Kyle C, Mackie C, Yates K, Duff E
Environ Pollut
. 2010 Nov;
159(2):416-22.
PMID: 21074917
Muscle tissue was collected from ewes and lambs derived from farms throughout Scotland and sample concentrations of five endocrine disrupting compound groups were determined. Farms of origin were categorised according...
5.
Rhind S, Kyle C, Mackie C, McDonald L, Zhang Z, Duff E, et al.
J Environ Monit
. 2010 Aug;
12(8):1582-93.
PMID: 20676422
Liver concentrations of selected pollutant classes were determined in groups of sheep fetuses and their dams, at 55 (Experiment 1) and 110 (Experiment 2) days of gestation (term = 145...
6.
Rhind S, Kyle C, Mackie C, McDonald L
J Environ Monit
. 2009 Aug;
11(8):1469-76.
PMID: 19657530
Fetal tissue concentrations of endocrine disrupting compounds (EDCs), and their relationship to maternal tissue concentrations, are largely unknown, in any species. In particular, the patterns of accumulation in the respective...
7.
WATKINS C, Mackellar A, Frew D, Mackie C, George A, Hopkins J, et al.
Parasite Immunol
. 2009 Jun;
31(6):304-11.
PMID: 19493210
Sheep scab is caused by the noninvasive mite, Psoroptes ovis, which initiates a profound pro-inflammatory skin response leading to lesion development. To investigate these early events between the skin and...
8.
Masungi C, Mensch J, Van Dijck A, Borremans C, Willems B, Mackie C, et al.
Pharmazie
. 2008 May;
63(3):194-9.
PMID: 18444507
The parallel artificial membrane permeability assay (PAMPA) is extensively used for the evaluation of early drug candidates. It is high throughput, low cost and is amenable to automation. This method...
9.
Nordquist R, Steckler T, Wettstein J, Mackie C, Spooren W
Psychopharmacology (Berl)
. 2008 Mar;
199(3):389-402.
PMID: 18322676
Rationale: The increasing awareness of the need to align clinical and preclinical research to facilitate rapid development of new drug therapies is reflected in the recent introduction of the term...
10.
Eichenbaum G, Pollock-Dove C, Nguyen J, Li S, Evans J, Borghys H, et al.
J Pharm Sci
. 2006 Feb;
95(4):883-95.
PMID: 16489607
In this paper, we present a preclinical approach for evaluating the feasibility of applying controlled-release (CR) oral drug delivery to increase the duration of exposure and lower the C(max) of...