C M Rodrigues
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Explore the profile of C M Rodrigues including associated specialties, affiliations and a list of published articles.
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37
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1192
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Recent Articles
11.
Kaemmerer W, Rodrigues C, Steer C, Low W
Neuroscience
. 2001 Mar;
103(3):713-24.
PMID: 11274790
It is not known why expression of a protein with an expanded polyglutamine region is pathogenic in spinocerebellar ataxia, Huntington's disease and several other neurodegenerative diseases. Dietary supplementation with creatine...
12.
Rodrigues C, Sola S, Brito M, Brondino C, Brites D, Moura J
Biochem Biophys Res Commun
. 2001 Feb;
281(2):468-74.
PMID: 11181071
Mitochondria have been implicated in the cytotoxicity of amyloid beta-peptide (A beta), which accumulates as senile plaques in the brain of Alzheimer's disease patients. Tauroursodeoxycholate (TUDC) modulates cell death, in...
13.
Rodrigues C, Sola S, Silva R, Brites D
Mol Med
. 2001 Jan;
6(11):936-46.
PMID: 11147571
Background: The pathogenesis of bilirubin encephalopathy and Alzheimer's disease appears to result from accumulation of unconjugated bilirubin (UCB) and amyloid-beta (Abeta) peptide, respectively, which may cause apoptosis. Permeabilization of the...
14.
Rodrigues C, Stieers C, Keene C, Ma X, Kren B, Low W, et al.
J Neurochem
. 2000 Nov;
75(6):2368-79.
PMID: 11080188
Ursodeoxycholic acid (UDCA) has been shown to be a strong modulator of the apoptotic threshold in both hepatic and nonhepatic cells. 3-Nitropropionic acid (3-NP), an irreversible inhibitor of succinate dehydrogenase,...
15.
Trembley J, Chen Z, Rodrigues C, Kren B, Steer C
Gene
. 2000 Sep;
255(1):93-104.
PMID: 10974569
Cyclin B1 is a key regulatory protein involved in cellular mitosis. We have cloned 1.8kb of DNA sequence upstream of the rat cyclin B1 gene translation start site from Rattus...
16.
Rodrigues C, Brites D, Serejo F, Costa A, Ramalho F, de Moura M
J Viral Hepat
. 2000 Jun;
7(3):175-83.
PMID: 10849259
The mechanisms of hepatocyte damage and the events that lead to high rates of chronic liver disease in hepatitis C virus (HCV) infection remain unclear. Recent in vitro studies have...
17.
18.
Rodrigues C, Ma X, Fan G, Kren B, Steer C
Cell Death Differ
. 1999 Oct;
6(9):842-54.
PMID: 10510466
The hydrophilic bile salt ursodeoxycholic acid (UDCA) is a potent inhibitor of apoptosis. In this paper, we further characterize the mechanism by which UDCA inhibits apoptosis induced by deoxycholic acid,...
19.
Rodrigues C, Steer C
Gastroenterology
. 1999 Aug;
117(3):732-6.
PMID: 10464152
No abstract available.
20.
Rodrigues C, Marin J, Brites D
Gut
. 1999 Aug;
45(3):446-52.
PMID: 10446117
Background: Data on meconium bile acid composition in newborn babies of patients with intrahepatic cholestasis of pregnancy (ICP) are relatively scant, and changes that occur on ursodeoxycholic acid (UDCA) administration...