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C M Lindgren

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Articles 17
Citations 1143
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Recent Articles
1.
Makrinou E, Drong A, Christopoulos G, Lerner A, Chapa-Chorda I, Karaderi T, et al.
Mol Cell Endocrinol . 2019 Oct; 500:110611. PMID: 31600550
Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age, whose aetiology remains unclear. To improve our understanding of the molecular mechanisms underlying the disease,...
2.
Schleinitz D, Kloting N, Lindgren C, Breitfeld J, Dietrich A, Schon M, et al.
Int J Obes (Lond) . 2013 May; 38(1):120-5. PMID: 23670221
Objective: We hypothesized that genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits. Methods: Adipose tissue (AT) mRNA expression...
3.
Drong A, Lindgren C, McCarthy M
Clin Pharmacol Ther . 2012 Oct; 92(6):707-15. PMID: 23047653
Type 2 diabetes (T2D) and obesity are complex disorders that constitute major public health problems. The evidence for familial aggregation of both T2D and obesity is substantial. To date, more...
4.
Herrera B, Lockstone H, Taylor J, Ria M, Barrett A, Collins S, et al.
Diabetologia . 2010 Mar; 53(6):1099-109. PMID: 20198361
Aims/hypothesis: MicroRNAs regulate a broad range of biological mechanisms. To investigate the relationship between microRNA expression and type 2 diabetes, we compared global microRNA expression in insulin target tissues from...
5.
Lappalainen T, Hannelius U, Salmela E, von Dobeln U, Lindgren C, Huoponen K, et al.
Ann Hum Genet . 2008 Dec; 73(1):61-73. PMID: 19040656
A population sample representing the current Swedish population was analysed for maternally and paternally inherited markers with the aim of characterizing genetic variation and population structure. The sample set of...
6.
Barber T, Bennett A, Groves C, Sovio U, Ruokonen A, Martikainen H, et al.
Diabetologia . 2008 May; 51(7):1153-8. PMID: 18478198
Aims/hypothesis: Variants in the fat-mass and obesity-associated gene (FTO) influence susceptibility to type 2 diabetes via an effect on adiposity/obesity. Given the important role of obesity in the aetiology of...
7.
Holmkvist J, Tojjar D, Almgren P, Lyssenko V, Lindgren C, Isomaa B, et al.
Diabetologia . 2007 Oct; 50(12):2467-75. PMID: 17934712
Aims/hypothesis: Glucose-stimulated insulin secretion is dependent on the electrical activity of beta cells; hence, genes encoding beta cell ion channels are potential candidate genes for type 2 diabetes. The gene...
8.
Ollikainen M, Hannelius U, Lindgren C, Abdel-Rahman W, Kere J, Peltomaki P
Oncogene . 2007 Jan; 26(31):4541-9. PMID: 17260015
Mutations in the DNA mismatch repair gene MLH1 are a major cause of hereditary nonpolyposis colorectal cancer (HNPCC). No mutant phenotype is observed before the wild-type (wt) allele is somatically...
9.
Malerba G, Lindgren C, Xumerle L, Kiviluoma P, Trabetti E, Laitinen T, et al.
Clin Exp Allergy . 2007 Jan; 37(1):83-9. PMID: 17210045
Background: Several genome scans have reported linkage of markers on chromosome 7p with asthma and related phenotypes in different populations. A fine mapping in Finnish and French-Canadian populations has associated...
10.
Holmkvist J, Cervin C, Lyssenko V, Winckler W, Anevski D, Cilio C, et al.
Diabetologia . 2006 Oct; 49(12):2882-91. PMID: 17033837
Aims/hypothesis: Mutations in the hepatocyte nuclear factor 1-alpha gene (HNF-1alpha, now known as the transcription factor 1 gene [TCF1]) cause the most common monogenic form of diabetes, MODY3, but it...