C M Les
Overview
Explore the profile of C M Les including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
141
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Recent Articles
1.
Drum M, Les C, Park R, Norrdin R, McIlwraith C, Kawcak C
Bone
. 2008 Oct;
44(2):316-9.
PMID: 18852072
The purpose of this study was to compare subchondral bone density obtained using quantitative computed tomography with ash density values from intact equine joints, and to determine if there are...
2.
Yeni Y, Yerramshetty J, Akkus O, Pechey C, Les C
Calcif Tissue Int
. 2006 Jul;
78(6):363-71.
PMID: 16830201
Raman spectroscopy provides valuable information on the physicochemical properties of hard tissues. While the technique can analyze tissues in their native state, analysis of fixed, embedded, and sectioned specimens may...
3.
Les C, Vance J, Christopherson G, Turner A, Divine G, Fyhrie D
J Orthop Res
. 2005 Jul;
23(4):869-76.
PMID: 16023002
Changes in bone mineral density associated with estrogen depletion in humans do not account for all of the associated change in fracture risk, and it is possible that some of...
4.
Dong X, Yeni Y, Zhang B, Les C, Gibson G, Fyhrie D
Calcif Tissue Int
. 2005 May;
77(1):37-44.
PMID: 15906016
Insulin-like growth factor-I (IGF-I), abundant in bone matrix, is believed to play an important role during bone development and remodeling. To our knowledge, however, few studies have addressed the relationship...
5.
MacLeay J, Olson J, Enns R, Les C, Toth C, Wheeler D, et al.
Calcif Tissue Int
. 2004 Dec;
75(5):431-7.
PMID: 15592799
Dietary-induced metabolic acidosis (DIMA) may be a significant confounder in the development of osteoporosis. Diets that are acidifying are typically rich in proteins and grains and relatively poor in fruits...
6.
Les C, Spence C, Vance J, Christopherson G, Patel B, Turner A, et al.
Bone
. 2004 Sep;
35(3):729-38.
PMID: 15336610
Significant decreases in ovine compact bone viscoelastic properties (specifically, stress-rate sensitivity, and damping efficiency) are associated with three years of ovariectomy and are particularly evident at higher frequencies [Proc. Orthop....
7.
Martinelli M, Eurell J, Les C, Fyhrie D, Bennett D
Equine Vet J
. 2002 Jul;
34(3):274-8.
PMID: 12108746
Although there are many studies in the equine literature focused on articular diseases and the aetiology of osteoarthritis, few have concentrated on normal articular structures and how they change with...
8.
Les C, Whalen R, Beaupre G, Yan C, Cleek T, Wills J
J Orthop Res
. 2002 Jun;
20(3):633-41.
PMID: 12038641
Changes in the material characteristics of bone marrow with aging can be a significant source of error in measurements of bone density when using X-ray and ultrasound imaging modalities. In...
9.
Les C, Stover S, Keyak J, Taylor K, Kaneps A
J Orthop Res
. 2002 Jun;
20(3):607-14.
PMID: 12038638
Our hypothesis was that post-yield mechanical behavior of compact bone material in compression, defined as the stress, strain, or energy absorbed between 0.2% strain-offset and the point of maximum stress,...
10.
Keyak J, Rossi S, Jones K, Les C, Skinner H
Med Eng Phys
. 2002 Jan;
23(9):657-64.
PMID: 11755810
Finite element (FE) models of the proximal femur are often used to study hip fracture. To interpret the results of these models, it is important to know whether the models...