C L Walker
Overview
Explore the profile of C L Walker including associated specialties, affiliations and a list of published articles.
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95
Citations
1262
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Recent Articles
1.
Hasanov E, Chen G, Chowdhury P, Weldon J, Ding Z, Jonasch E, et al.
Oncogene
. 2017 Jan;
36(24):3450-3463.
PMID: 28114281
The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being its...
2.
McCampbell A, Mittelstadt M, Dere R, Kim S, Zhou L, Djordjevic B, et al.
Curr Mol Med
. 2016 Feb;
16(3):252-65.
PMID: 26917264
Endometrial carcinoma (EC) exhibits the strongest association with obesity of all cancers. Growth of these tumors is driven by PI3K/AKT activation, and opposed by tumor suppressors, including the tuberous sclerosis...
3.
Zhou L, Liu X, Sun M, Zhang X, German P, Bai S, et al.
Oncogene
. 2015 Sep;
35(21):2687-97.
PMID: 26364599
Antiangiogenic therapy resistance occurs frequently in patients with metastatic renal cell carcinoma (RCC). The purpose of this study was to understand the mechanism of resistance to sunitinib, an antiangiogenic small...
4.
Ho T, Park I, Zhao H, Tong P, Champion M, Yan H, et al.
Oncogene
. 2015 Jun;
35(12):1565-74.
PMID: 26073078
Mutations in SETD2, a histone H3 lysine trimethyltransferase, have been identified in clear cell renal cell carcinoma (ccRCC); however it is unclear if loss of SETD2 function alters the genomic...
5.
Liu X, Yao J, Tripathi D, Ding Z, Xu Y, Sun M, et al.
Oncogene
. 2014 Jul;
34(19):2450-60.
PMID: 24998849
Autophagy is a conserved process involved in lysosomal degradation of protein aggregates and damaged organelles. The role of autophagy in cancer is a topic of intense debate, and the underlying...
6.
Peng H, Liu J, Sun Q, Chen R, Wang Y, Duan J, et al.
Oncogene
. 2012 Oct;
32(39):4702-11.
PMID: 23108404
The protein complex of tuberous sclerosis complex (TSC)1 and TSC2 tumor suppressors is a key negative regulator of mammalian target of rapamycin (mTOR). Hyperactive mTOR signaling due to the loss-of-function...
7.
8.
Greathouse K, Cook J, Lin K, Davis B, Berry T, Bredfeldt T, et al.
Reprod Sci
. 2008 Nov;
15(8):765-78.
PMID: 19017814
Environmental exposures during development can alter susceptibility later in life to adult diseases including uterine leiomyoma, a phenomenon termed developmental reprogramming. The goal of this study was to identify genes...
9.
Schwalbe N, Wells W, Geaneotes A, Forcellina A, Lee M, Dicola L, et al.
Int J Tuberc Lung Dis
. 2008 Sep;
12(10):1173-81.
PMID: 18812048
Background: The successful introduction of new drugs into low- and middle-income countries requires an understanding of the existing market size and market dynamics for the therapeutic area of interest. The...
10.
Ptacek T, Song C, Walker C, Sell S
Cancer Genet Cytogenet
. 2007 Apr;
174(2):116-20.
PMID: 17452252
Uterine leiomyoma (UL) is a benign, smooth muscle tumor of the uterus affecting a significant proportion of women of reproductive age. Deletions involving chromosome 7q22 are common in UL and...