C L Tannahill
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Explore the profile of C L Tannahill including associated specialties, affiliations and a list of published articles.
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14
Citations
223
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Recent Articles
1.
McAuliffe P, Murday M, Efron P, Scumpia P, Ungaro R, Abouhamze A, et al.
Gene Ther
. 2005 Oct;
13(3):276-82.
PMID: 16251998
Targeted expression of interleukin-10 (IL-10) has been proposed as a means to suppress acute and chronic inflammation. We explored the capacity of targeted adenoviral expression of human or viral IL-10...
2.
Oberholzer C, Oberholzer A, Bahjat F, Minter R, Tannahill C, Abouhamze A, et al.
Proc Natl Acad Sci U S A
. 2001 Sep;
98(20):11503-8.
PMID: 11553765
Sepsis remains a significant clinical conundrum, and recent clinical trials with anticytokine therapies have produced disappointing results. Animal studies have suggested that increased lymphocyte apoptosis may contribute to sepsis-induced mortality....
3.
Minter R, Ferry M, Murday M, Tannahill C, Bahjat F, Oberholzer C, et al.
J Immunol
. 2001 Jul;
167(2):1053-9.
PMID: 11441115
Adenovirus (Ad) gene therapy has been proposed as a drug-delivery system for the targeted administration of protein-based therapies, including growth factors and biological response modifiers. However, inflammation associated with Ad...
4.
Norman J, Denham W, Denham D, Yang J, Carter G, Abouhamze A, et al.
Gene Ther
. 2000 Sep;
7(16):1425-30.
PMID: 10981671
Cationic liposome and plasmid-mediated gene transfer has emerged as a novel technique for the targeted delivery of protein-based therapies in acute inflammatory diseases. However, concerns have arisen that cationic liposomes...
5.
Josephs M, Bahjat F, Fukuzuka K, Ksontini R, Solorzano C, Edwards 3rd C, et al.
Am J Physiol Regul Integr Comp Physiol
. 2000 May;
278(5):R1196-201.
PMID: 10801287
Tumor necrosis factor (TNF)-alpha and Fas ligand (FasL) are trimeric proteins that induce apoptosis through similar caspase-dependent pathways. Hepatocytes are particularly sensitive to inflammation-induced programmed cell death, although the contribution...
6.
Minter R, Rectenwald J, Fukuzuka K, Tannahill C, La Face D, Tsai V, et al.
J Immunol
. 1999 Dec;
164(1):443-51.
PMID: 10605041
Recombinant adenovirus-mediated gene therapy has demonstrated great promise for the delivery of genes to the pulmonary epithelium. However, dose-dependent inflammation and local immune responses abbreviate transgene expression. The purpose of...
7.
Tannahill C, Fukuzuka K, Marum T, Abouhamze Z, MacKay S, Copeland 3rd E, et al.
Surgery
. 1999 Aug;
126(2):349-57.
PMID: 10455905
Background: Tumor necrosis factor-alpha (TNF-alpha) is a member of a large family of predominantly homotrimeric type II membrane-associated proteins with both proinflammatory and apoptosis-inducing properties. Although TNF-alpha expression has been...
8.
MacKay S, Tannahill C, Auffenberg T, Ksontini R, Copeland 3rd E, Moldawer L
Biochem Biophys Res Commun
. 1999 Jul;
260(2):390-7.
PMID: 10403780
A hammerhead ribozyme directed against murine TNFalpha (mTNFalpha) mRNA has been constructed. In vitro studies showed that this ribozyme was released from the parent molecule by flanking cis-acting hammerhead and...
9.
MacKay S, Auffenberg T, Tannahill C, Ksontini R, Josephs M, Nowak M, et al.
Ann Surg
. 1998 Jun;
227(6):781-9.
PMID: 9637541
Objective: To determine if transfection of SW48 colon cancer cells with the type II transforming growth factor-beta (TGF-beta) receptor restores growth inhibition and reverses the in vitro and in vivo...
10.
Thornton F, Schaffer M, Witte M, Moldawer L, MacKay S, Abouhamze A, et al.
Biochem Biophys Res Commun
. 1998 Jun;
246(3):654-9.
PMID: 9618268
Inducible nitric oxide synthase (iNOS) is expressed during cutaneous wound repair. Mounting evidence suggests that wound nitric oxide (NO) augments collagen accumulation. We hypothesized that in vivo transfection of wound...