C L Noble
Overview
Explore the profile of C L Noble including associated specialties, affiliations and a list of published articles.
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12
Citations
272
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Recent Articles
1.
Ho G, Aird R, Liu B, Boyapati R, Kennedy N, Dorward D, et al.
Mucosal Immunol
. 2017 Apr;
11(1):120-130.
PMID: 28401939
The multidrug resistance-1 (MDR1) gene encodes an ATP-dependent efflux transporter that is highly expressed in the colon. In mice, loss of MDR1 function results in colitis with similarities to human...
2.
Kennedy N, Rhatigan E, Arnott I, Noble C, Shand A, Satsangi J, et al.
Aliment Pharmacol Ther
. 2013 Oct;
38(10):1255-66.
PMID: 24117596
Background: Thiopurines maintain remission and modify disease course in inflammatory bowel disease. Use is limited by intolerance and subsequent drug withdrawal in approximately 17% of patients treated with azathioprine. Previous...
3.
What is the risk that a child will develop inflammatory bowel disease if 1 or both parents have IBD?
Noble C, Arnott I
Inflamm Bowel Dis
. 2008 Sep;
14 Suppl 2:S22-3.
PMID: 18816708
No abstract available.
4.
Noble C, Abbas A, Cornelius J, Lees C, Ho G, Toy K, et al.
Gut
. 2008 Jun;
57(10):1398-405.
PMID: 18523026
Objective: To investigate differential intestinal gene expression in patients with ulcerative colitis and in controls. Design: Genome-wide expression study (41,058 expression sequence tags, 215 biopsies). Setting: Western General Hospital, Edinburgh,...
5.
Noble C, McCullough J, Ho W, Lees C, Nimmo E, Drummond H, et al.
Aliment Pharmacol Ther
. 2008 Jan;
27(7):588-96.
PMID: 18194505
Background: Osteoporosis is a recognized complication of inflammatory bowel disease (IBD). Aim To investigate the role of environmental factors and vitamin D receptor (VDR) variants on the prevalence of osteoporosis....
6.
Din S, Cochrane C, Noble C, Satsangi J, Arnott I
Inflamm Bowel Dis
. 2007 Oct;
14(1):143-5.
PMID: 17932978
No abstract available.
7.
Browning B, Annese V, Barclay M, Bingham S, Brand S, Buning C, et al.
J Med Genet
. 2007 Aug;
45(1):36-42.
PMID: 17693570
Background: DLG5 p.R30Q has been reported to be associated with Crohn disease (CD), but this association has not been replicated in most studies. A recent analysis of gender-stratified data from...
8.
Lees C, Heys D, Ho G, Noble C, Shand A, Mowat C, et al.
Aliment Pharmacol Ther
. 2007 Jul;
26(3):411-9.
PMID: 17635376
Background: Forty per cent of patients with acute severe ulcerative colitis will not respond to intravenous corticosteroids and require second-line medical therapy or colectomy. A recent controlled trial has suggested...
9.
Russell R, Drummond H, Nimmo E, Anderson N, Noble C, WILSON D, et al.
Gut
. 2006 Feb;
55(8):1114-23.
PMID: 16469794
Background And Aims: The OCTN1 (SLC22A4 1672C-->T) and OCTN2 (SLC22A5 -207G-->C) variants within the IBD5 locus have been associated with susceptibility to adult onset Crohn's disease (CD), but their contribution...
10.
Noble C, Nimmo E, Drummond H, Smith L, Arnott I, Satsangi J
Gut
. 2005 Apr;
54(10):1416-20.
PMID: 15843420
Introduction: Recent data have suggested that specific haplotypic variants of the DLG5 gene on chromosome 10q23 may be associated with susceptibility to inflammatory bowel disease (IBD) in Germany. Haplotype D,...