C L Flemming
Overview
Explore the profile of C L Flemming including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
50
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Recent Articles
1.
Flemming C, Patel P, Box G, Eccles S, Collins M
Cytokine
. 1997 May;
9(5):328-32.
PMID: 9195131
The murine fibrosarcoma FS29 can be more efficiently killed by syngeneic lymphocytes when it has been engineered to secrete either interferon gamma (IFN-gamma), or interleukin 2 (IL-2). The mechanisms by...
2.
de Wit D, Flemming C, Harris J, Palmer K, Moore J, Gore M, et al.
Clin Exp Immunol
. 1996 Aug;
105(2):353-9.
PMID: 8706345
Recent studies have demonstrated that rodent tumour cells engineered to secrete a variety of cytokines, or to express foreign antigens, MHC molecules or co-stimulatory molecules, are rejected by syngeneic animals....
3.
Patel P, Flemming C, Fisher C, Porter C, Thomas J, Gore M, et al.
Hum Gene Ther
. 1994 May;
5(5):577-84.
PMID: 8054375
This study aimed to determine the feasibility of producing patient-specific, interleukin-2 (IL-2)-secreting tumor cell vaccines for the treatment of metastatic melanoma. Primary tumor cell cultures were established from 26/33 resected...
4.
Patel P, Flemming C, Russell S, Eccles S, Collins M
J Immunother Emphasis Tumor Immunol
. 1993 Nov;
14(4):310-3.
PMID: 8280713
Cytokine gene therapy for cancer could involve either the direct delivery of cytokine genes to established tumours to stimulate their rejection or the injection of cytokine-secreting tumour cells to stimulate...
5.
Patel P, Flemming C, Russell S, McKay I, MacLennan K, Box G, et al.
Br J Cancer
. 1993 Aug;
68(2):295-302.
PMID: 8347485
Engineering of a variety of rodent tumour cells to secrete either interleukin 2 (IL-2), or interleukin 4 (IL-4), has been demonstrated to reduce their tumorigenicity. However the mechanisms of action...
6.
Perkins G, Flemming C, Kabat D, Collins M
Int Immunol
. 1993 May;
5(5):541-9.
PMID: 8318457
This report addresses the role of individual IL-2 binding proteins of the IL-2 receptor in the stimulation of cell proliferation by IL-2. Murine IL-3-dependent cell lines were established which expressed...
7.
Flemming C, Russell S, Collins M
Eur J Immunol
. 1993 Apr;
23(4):917-21.
PMID: 8458377
Mutation of Asp20 in human interleukin-2 (IL-2) to Lys is known to result in an IL-2 molecule with unchanged binding to the p55 subunit of the IL-2 receptor, but with...
8.
Russell S, Brandenburger A, Flemming C, Collins M, Rommelaere J
J Virol
. 1992 May;
66(5):2821-8.
PMID: 1560527
The prototype strain of minute virus of mice [MVM(p)] is an autonomous parvovirus with a tropism for cells expressing a neoplastically transformed phenotype. To generate gene transfer vectors for tumor-specific...
9.
Stokes G, Monaghan J, Flemming C, Johnston H, Jones M, PINKERTON G, et al.
Clin Sci (Lond)
. 1992 May;
82(5):505-12.
PMID: 1317759
1. Studies were undertaken in pre-menopausal women to examine the effects of treatment with standard oestrogen-progestogen and progestogen-ony oral contraceptives on erythrocyte Na+,K+ co-transport and Na(+)-Na+ countertransport over 3- and...
10.
Collins M, Patel P, Flemming C, Eccles S
Bone Marrow Transplant
. 1992 Jan;
9 Suppl 1:171-3.
PMID: 1504662
No abstract available.