C L Farrell
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Explore the profile of C L Farrell including associated specialties, affiliations and a list of published articles.
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61
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1185
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Recent Articles
1.
Kurrimbux D, Gaffen Z, Farrell C, Martin D, Thomas S
Neuroscience
. 2003 Dec;
123(2):527-36.
PMID: 14698759
Leptin is a 16 kDa hormone that is produced by adipose tissue and has a central effect on food intake and energy homeostasis. The ability of leptin to cross the...
2.
Dorr W, Spekl K, Farrell C
Cell Prolif
. 2002 Jul;
35 Suppl 1:86-92.
PMID: 12139711
The purpose of this study was to examine the effect of recombinant human keratinocyte growth factor (rHuKGF) on clinically manifest acute oral mucositis. The animal model utilized in this investigation...
3.
Farrell C, Rex K, Chen J, Bready J, DiPalma C, KAUFMAN S, et al.
Cell Prolif
. 2002 Jul;
35 Suppl 1:78-85.
PMID: 12139710
The epithelium of the oral cavity and small intestine of the gastrointestinal tract have a high rate of cell renewal and as such, are sensitive to cytotoxic therapies that kill...
4.
McCarthy T, Banks W, Farrell C, Adamu S, Derdeyn C, Snyder A, et al.
J Pharmacol Exp Ther
. 2002 May;
301(3):878-83.
PMID: 12023514
Human obesity may be caused by a resistance to circulating leptin. Evidence from rodents and humans suggests that a major component of this resistance is an impairment in the ability...
5.
Ziegler T, Gu L, Jonas C, Farrell C, Lacey D, Jones D, et al.
Transplantation
. 2001 Oct;
72(8):1354-62.
PMID: 11685103
Background: Reactive oxygen species (ROS) and glutathione (GSH) depletion contribute to organ injury after bone marrow transplantation (BMT). Keratinocyte growth factor (KGF) ameliorates graft-versus-host disease (GVHD)-associated organ injury in murine...
6.
Potten C, OShea J, Farrell C, Rex K, Booth C
Cell Growth Differ
. 2001 May;
12(5):265-75.
PMID: 11373273
Keratinocyte growth factor (KGF) administered on a daily basis for 3 or more days can result in dramatic changes in tissue architecture, particularly the thickness in oral epithelia, and can...
7.
Thomas S, Preston J, Wilson M, Farrell C, Segal M
Brain Res
. 2001 Mar;
895(1-2):283-90.
PMID: 11259792
Leptin is secreted by adipose tissue and thought to regulate appetite at the central level. Several studies have explored the central nervous system (CNS) entry of this peptide across the...
8.
Dorr W, Noack R, Spekl K, Farrell C
Int J Radiat Biol
. 2001 Mar;
77(3):341-7.
PMID: 11258848
Purpose: The aim was to quantify the effect of recombinant human keratinocyte growth factor (rhKGF) on acute oral mucositis induced by a single radiation dose, simulating accidental radiation exposure. Material...
9.
Farrell C, Rex K, KAUFMAN S, DiPalma C, Chen J, Scully S, et al.
Int J Radiat Biol
. 2001 Feb;
75(5):609-20.
PMID: 10374943
Purpose: To investigate the effects of keratinocyte growth factor (KGF) on the structure of the stratified squamous epithelium of the tongue, buccal mucosa and oesophagus of normal and irradiated mice....
10.
Panoskaltsis-Mortari A, Taylor P, Rubin J, Uren A, Welniak L, Murphy W, et al.
Blood
. 2000 Dec;
96(13):4350-6.
PMID: 11110712
We have previously shown that pretreatment of mice with keratinocyte growth factor (KGF), an epithelial tissue repair factor, can ameliorate graft-versus-host disease (GVHD) after intensive chemoradiotherapeutic conditioning and allogeneic bone...