C L Bethea
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Explore the profile of C L Bethea including associated specialties, affiliations and a list of published articles.
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98
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1181
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Recent Articles
1.
Thompson M, Macmillan L, Bethea C, Williams L, Abee C, Scammell J
Am J Primatol
. 2020 Jan;
19(3):175-181.
PMID: 31964009
Determination of squirrel monkey prolactin by immunoassay has been hampered by the lack of antiserum specific to prolactin from this species. As an alternate method, we have investigated whether the...
2.
Bethea C, Phu K, Kim A, Reddy A
Neuroscience
. 2015 Jun;
301:576-89.
PMID: 26086546
A number of studies have shown that mutations or deletions of the monoamine oxidase-A (MAO-A) gene cause elevated CNS serotonin and elevated impulsive aggression in humans and animal models. In...
3.
Bethea C, Reddy A
Mol Psychiatry
. 2015 Jan;
20(12):1565-78.
PMID: 25600110
Depression often accompanies the perimenopausal transition and it often precedes overt symptomology in common neurodegenerative diseases (NDDs, such as Alzheimer's, Parkinson's, Huntington, amyotrophic lateral sclerosis). Serotonin dysfunction is frequently found...
4.
Bethea C, Coleman K, Phu K, Reddy A, Phu A
Neuroscience
. 2014 Jun;
274:341-56.
PMID: 24909896
Androgen administration to castrated individuals was purported to decrease activity in the serotonin system. However, we found that androgen administration to castrated male macaques increased fenfluramine-induced serotonin release as reflected...
5.
Bethea C, Kim A, Reddy A, Chin A, Bethea S, Cameron J
J Neuroendocrinol
. 2014 Mar;
26(5):267-81.
PMID: 24617839
The present study examined the effect of short-term psychosocial and metabolic stress in a monkey model of stress-induced amenorrhaea on the hypothalamic-pituitary-gonadal axis. KISS1 expression was determined by in situ...
6.
Alcin E, Sahu A, Ramaswamy S, Hutz E, Keen K, Terasawa E, et al.
J Neuroendocrinol
. 2013 Jan;
25(5):488-96.
PMID: 23331967
Tonic gonadotrophin secretion throughout the menstrual cycle is regulated by the negative-feedback actions of ovarian oestradiol (E₂) and progesterone. Although kisspeptin neurones in the arcuate nucleus (ARC) of the hypothalamus...
7.
Rivera H, Bethea C
Neuroscience
. 2012 Feb;
208:27-40.
PMID: 22342969
Dendritic spines are the basic structural units of neuronal plasticity. Intracellular signaling cascades that promote spinogenesis have centered on RhoGTPases. We found that ovarian steroids increase gene expression of RhoGTPases...
8.
Bogdan R, Fitzgibbon H, Woolverton W, Bethea C, Iyo A, Stockmeier C, et al.
Neurosci Lett
. 2011 Aug;
503(2):83-6.
PMID: 21871532
TREK1 is a widely expressed background potassium channel. Similar to mice treated with selective serotonin reuptake inhibitors (SSRIs), TREK1 knockout mice are resistant to depression-like behavior and have elevated serotonin...
9.
Long-term ovariectomy decreases serotonin neuron number and gene expression in free ranging macaques
Bethea C, Smith A, Centeno M, Reddy A
Neuroscience
. 2011 Jul;
192:675-88.
PMID: 21763405
The serotonin system responds to the ovarian steroids, estradiol (E) and progesterone (P), in women and female animal models. In macaques, ovarian steroid administration to ovariectomized (Ovx) individuals improves serotonin...
10.
Sanchez R, Reddy A, Bethea C
Neuroscience
. 2010 Sep;
171(3):893-909.
PMID: 20833230
A significant number of postmenopausal women report increased anxiety and vulnerability to stress, which has been linked to decreased secretion of ovarian steroids. Communication between the serotonin system and the...